Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Rizatriptan
Drug ID BADD_D01957
Description Rizatriptan is a triptan drug used for the treatment of migraine headaches. It is a selective 5-hydroxytryptamine1 receptor subtype agonist.
Indications and Usage For treatment of acute migraine attacks with or without aura.
Marketing Status approved
ATC Code N02CC04
DrugBank ID DB00953
KEGG ID D08485
MeSH ID C093622
PubChem ID 5078
TTD Drug ID D0S9MU
NDC Product Code 33342-088; 71335-1352; 62938-0020; 65977-0067; 33342-087; 63850-7138; 63850-7119
UNII 51086HBW8G
Synonyms rizatriptan | N,N-dimethyl-2-(5-(1,2,4-triazol-1-ylmethyl)-1H-indole-3-yl)ethylamine | rizatriptan benzoate | MK 0462 | MK-0462 | MK-462 | MK 462 | L 705,126 | L-705,126 | L-705126 | L 705126 | Maxalt
Chemical Information
Molecular Formula C15H19N5
CAS Registry Number 144034-80-0
SMILES CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001---
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.0020.000805%
Abdominal pain upper07.01.05.0030.000668%
Abortion18.01.01.0010.000136%-
Aggression19.05.01.0010.000136%-
Agitation17.02.05.012; 19.06.02.0010.000546%
Akinesia17.01.02.003---
Anaphylactic shock10.01.07.002; 24.06.02.004---
Anaphylactoid reaction10.01.07.003; 24.06.03.007---
Angina pectoris02.02.02.002; 24.04.04.0020.000136%
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Anxiety19.06.02.0020.000737%
Arrhythmia02.03.02.001---
Arteriospasm coronary02.02.02.005; 12.02.01.031; 24.04.04.005---
Arthralgia15.01.02.001--
Asthenia08.01.01.001---
Ataxia08.01.02.004; 17.02.02.001--
Aura17.02.07.011---
Blindness unilateral06.02.10.007; 17.17.01.016---
Blood pressure increased13.14.03.005---
Body temperature increased13.15.01.001---
Bradycardia02.03.02.002---
Bradykinesia17.01.02.004---
Cerebral infarction17.08.01.004; 24.04.06.0020.000136%-
Cerebrovascular accident17.08.01.007; 24.03.05.001--
Chest discomfort02.02.02.009; 08.01.08.019; 22.12.02.0020.000709%-
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.0030.000846%-
Chills08.01.09.001; 15.05.03.0160.000436%
Colitis ischaemic07.08.01.004; 24.04.08.0120.000436%-
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