Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Risedronate sodium
Drug ID BADD_D01949
Description Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label][A959].
Indications and Usage Risedronic acid is indicated for the treatment of osteoperosis in men, treatment of Paget's disease, treatment and prevention of osteoperosis in postmenopausal women, and treatment and prevention of glucocorticoid-induced osteoperosis[FDA Label].
Marketing Status approved; investigational
ATC Code M05BA07
DrugBank ID DB00884
KEGG ID D00942
MeSH ID D000068296
PubChem ID 4194514
TTD Drug ID D0PA5S
NDC Product Code 0430-0478; 0430-0979; 11722-077; 65096-0110; 47335-727; 60505-3097; 65862-519; 0093-3098; 33342-108; 47335-666; 0430-0472; 62331-017; 80426-042; 47335-928; 60723-041; 0430-0473; 53104-7653; 65862-518; 59762-0405; 63304-440; 65862-517; 16714-870; 0093-3100; 47335-667; 60505-3165; 65862-870; 0430-0970; 14998-0008; 65372-1113; 0093-3099; 33342-107; 33342-109; 59762-0406; 60505-3096; 68382-075; 71205-714; 0093-7771; 47335-668; 70771-1436; 0430-0487; 65977-0092; 59762-0407
UNII OFG5EXG60L
Synonyms Risedronic Acid | 1-Hydroxy-2-(3-pyridyl)ethylidene diphosphonate | Atelvia | Risedronate Sodium | 2-(3-pyridinyl)-1-hydroxyethylidene-bisphosphonate | 2-(3-pyridinyl)-1-hydroxyethylidenebisphosphonate | Risedronic Acid, Monosodium Salt | Actonel | Risedronate | Bisphosphonate Risedronate Sodium | Risedronate Sodium, Bisphosphonate | Sodium, Bisphosphonate Risedronate
Chemical Information
Molecular Formula C7H10NNaO7P2
CAS Registry Number 115436-72-1
SMILES C1=CC(=CN=C1)CC(O)(P(=O)(O)O)P(=O)(O)[O-].[Na+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.003--
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Arthralgia15.01.02.001--
Back pain15.03.04.005--
Bone pain15.02.01.001--
Bronchitis11.01.09.001; 22.07.01.001--
Constipation07.02.02.001--
Dermatitis bullous23.03.01.002--
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dyspepsia07.01.02.001--
Gastric ulcer07.04.03.002--
Headache17.14.01.001--
Influenza11.05.03.001; 22.07.02.001---
Iritis06.04.03.002; 10.02.01.022---
Muscle spasms15.05.03.004--
Musculoskeletal pain15.03.04.007--
Myalgia15.05.02.001--
Nausea07.01.07.001--
Oesophageal ulcer07.04.05.002--
Oesophagitis07.08.05.001--
Pain in extremity15.03.04.010--
Rash23.03.13.001---
Upper respiratory tract infection11.01.13.009; 22.07.03.011--
Uveitis06.04.03.003; 10.02.01.023--
Vomiting07.01.07.003--
Osteonecrosis of jaw15.02.04.010; 24.04.05.005--
Gastrointestinal tract irritation07.08.03.008---
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