Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Remifentanil hydrochloride
Drug ID BADD_D01923
Description Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Indications and Usage For use during the induction and maintenance of general anesthesia.
Marketing Status approved
ATC Code N01AH06
DrugBank ID DB00899
KEGG ID D01177
MeSH ID D000077208
PubChem ID 60814
TTD Drug ID D0T5OX
NDC Product Code 48954-724; 63323-723; 67457-912; 72078-035; 0143-9392; 50683-0550; 63323-724; 67457-198; 72078-036; 0143-9391; 67457-914; 12502-5343; 67457-913; 63323-725; 72078-034; 0143-9393
UNII 5V444H5WIC
Synonyms Remifentanil | 3-(4-Methoxycarbonyl-4-((1-oxopropyl)phenylamino)-1-piperidine)propanoic Acid Methyl Ester | Remifentanil Hydrochloride | Ultiva | Remifentanil Monohydrochloride | GI 87084B | GI87084B | GI-87084B
Chemical Information
Molecular Formula C20H29ClN2O5
CAS Registry Number 132539-07-2
SMILES CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC(=O)OC)C(=O)OC.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Cough22.02.03.001--
Dermatitis23.03.04.002---
Diarrhoea07.02.01.001--
Disorientation17.02.05.015; 19.13.01.002---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dry mouth07.06.01.002--
Dyskinesia17.01.02.006--
Dyspepsia07.01.02.001--
Dysphagia07.01.06.003--
Dysphoria19.04.02.004---
Dyspnoea02.11.05.003; 22.02.01.004--
Dysuria20.02.02.002--
Electrocardiogram abnormal13.14.05.001---
Electrolyte imbalance14.05.01.002---
Erythema23.03.06.001---
Eyelid ptosis06.05.01.002; 17.17.02.004---
Feeling abnormal08.01.09.014---
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Gastrooesophageal reflux disease07.02.02.003--
Gastrointestinal disorder07.11.01.001---
Haematochezia07.12.02.003; 24.07.02.012---
Haematuria20.02.01.006; 21.10.01.018; 24.07.01.047--
Haemoglobin13.01.05.018---
Haemoptysis02.11.04.009; 22.02.03.004; 24.07.01.006---
Hallucination19.10.04.003--
Headache17.14.01.001--
Hepatic function abnormal09.01.02.001---
Hiccups07.01.06.009; 22.12.01.001--
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