Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Quinaprilat
Drug ID BADD_D01892
Description The active metabolite of the prodrug [quinapril].
Indications and Usage Not Available
Marketing Status experimental
ATC Code Not Available
DrugBank ID DB14217
KEGG ID D03773
MeSH ID C054501
PubChem ID 107994
TTD Drug ID Not Available
NDC Product Code Not Available
UNII 34SSX5LDE5
Synonyms quinaprilat | 2-(2-((1-carboxy-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid | quinaprilat, (3S-(2(R*(R*)),3R*))-isomer | CI 928 | CI-928
Chemical Information
Molecular Formula C23H26N2O5
CAS Registry Number 82768-85-2
SMILES CC(C(=O)N1CC2=CC=CC=C2CC1C(=O)O)NC(CCC3=CC=CC=C3)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.0010.006163%-
Abdominal pain07.01.05.002--
Acute myocardial infarction02.02.02.001; 24.04.04.0010.002719%-
Agranulocytosis01.02.03.001---
Alopecia23.02.02.001--
Amblyopia06.02.01.001---
Anaphylactic reaction10.01.07.001; 24.06.03.0060.002719%
Anaphylactic shock10.01.07.002; 24.06.02.004---
Anaphylactoid reaction10.01.07.003; 24.06.03.007---
Angina pectoris02.02.02.002; 24.04.04.0020.001813%
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.0010.023382%-
Arrhythmia02.03.02.001---
Arthralgia15.01.02.001--
Asthenia08.01.01.0010.004894%-
Back pain15.03.04.005--
Blood urea increased13.13.01.006---
Cardiac failure congestive02.05.01.0020.009969%-
Cardiogenic shock02.05.01.003; 24.06.02.006---
Cerebrovascular accident17.08.01.007; 24.03.05.0010.007250%
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.0030.003988%-
Condition aggravated08.01.03.0040.003625%-
Constipation07.02.02.001--
Coronary artery disease02.02.01.001; 24.04.04.0060.005438%-
Cough22.02.03.0010.036976%
Dermatitis23.03.04.002---
Dermatitis exfoliative10.01.01.004; 23.03.07.001--
Dermatomyositis10.04.04.027; 15.05.01.002; 23.03.02.001---
Diabetes mellitus05.06.01.001; 14.06.01.0010.001813%-
Diarrhoea07.02.01.001--
Discomfort08.01.08.003---
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