| Pharmaceutical Information |
| Drug Name |
Pyrilamine |
| Drug ID |
BADD_D01885 |
| Description |
Mepyramine, or pyrilamine, targets the H1 receptor. It is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect. It has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered to be an unapproved prescription medication used for cough, cold, or allergic conditions. |
| Indications and Usage |
Indicated for the treatment of allergic conditions, symptomatic relief of hypersensitivity reaction, and treatment of pruritic skin disorders. |
| Marketing Status |
approved; vet_approved |
| ATC Code |
R06AC01; D04AA02 |
| DrugBank ID |
DB06691
|
| KEGG ID |
D08183; D05660
|
| MeSH ID |
D011738
|
| PubChem ID |
4992
|
| TTD Drug ID |
D08JZS
|
| NDC Product Code |
66620-100 |
| UNII |
HPE317O9TL
|
| Synonyms |
Pyrilamine | Mepyramine | Pyranisamine | Kriptin | Mepyramine Maleate | Maleate, Mepyramine | Pyrilamine Maleate | Maleate, Pyrilamine | Boots Bite & Sting Relief | Anthisan |
|
| Chemical Information |
| Molecular Formula |
C17H23N3O |
| CAS Registry Number |
91-84-9 |
| SMILES |
CN(C)CCN(CC1=CC=C(C=C1)OC)C2=CC=CC=N2 |
| Chemical Structure |
|
|
| ADRs Induced by Drug |
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*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
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|
| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
| Skin sensitisation | 10.02.01.038; 23.03.03.052 | - | - | - |
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