Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Proparacaine hydrochloride
Drug ID BADD_D01863
Description Proparacaine is a topical anesthetic drug of the amino ester group. It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt.
Indications and Usage Used as a local (ophthalmic) anesthetic.
Marketing Status approved; vet_approved
ATC Code S01HA04
DrugBank ID DB00807
KEGG ID D02098
MeSH ID C005717
PubChem ID 517321
TTD Drug ID D0Q7ZG
NDC Product Code 0998-0016; 61314-016; 68071-4368; 0404-7199; 51552-1450; 17478-263; 50090-1923; 70518-3408; 13985-611; 24208-730; 17205-340; 76003-3500
UNII U96OL57GOY
Synonyms proxymetacaine | benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester | proparacaine | proxymethacaine | 2-(diethylamino)ethyl 3-amino-4-propoxybenzoate | Alcaine | Chibro-Kerakain | Kainair | Kéracaine | proxymetacaine hydrochloride | proparacaine HCl | proxymetacaine monohydrochloride | benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester, monohydrochloride*benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester, monohydrochloride | proparacaine hydrochloride | 2-(diethylamino)ethyl 3-amino-4-propoxybenzoate monohydrochloride | Ocu-Caine | Ophthaine | Ophthetic | Parcaine | Proparakain-POS | AK-Taine | Minims Proxymetacaine Hydrochloride
Chemical Information
Molecular Formula C16H27ClN2O3
CAS Registry Number 5875-06-9
SMILES CCCOC1=C(C=C(C=C1)C(=O)OCCN(CC)CC)N.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Burning sensation08.01.09.029; 17.02.06.001---
Dermatitis contact10.01.01.003; 12.03.01.040; 23.03.04.004---
Iritis06.04.03.002; 10.02.01.022---
Keratitis06.04.02.002--
Pain08.01.08.004--
Conjunctival hyperaemia06.04.01.004---
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