Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Propantheline
Drug ID BADD_D01860
Description A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking.
Indications and Usage For the treatment of enuresis. It has also been used for hyperhidrosis, and cramps or spasms of the stomach, intestines or bladder.
Marketing Status approved
ATC Code A03AB05
DrugBank ID DB00782
KEGG ID D00481
MeSH ID D011413
PubChem ID 4934
TTD Drug ID D0V5ZZ
NDC Product Code Not Available
UNII 1306V2B0Q8
Synonyms Propantheline | Propantheline Bromide | Bromide, Propantheline | Probanthine | Pro-Banthine | Pro Banthine
Chemical Information
Molecular Formula C23H30NO3+
CAS Registry Number 298-50-0
SMILES CC(C)[N+](C)(CCOC(=O)C1C2=CC=CC=C2OC3=CC=CC=C13)C(C)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Rash23.03.13.001---
Salivary hypersecretion07.06.01.009---
Somnolence17.02.04.006; 19.02.05.003--
Tachycardia02.03.02.007---
Tension19.06.02.005---
Thirst08.01.09.021; 14.03.02.007---
Urinary hesitation20.02.02.009---
Urinary retention20.02.02.011--
Urticaria10.01.06.001; 23.04.02.001--
Vision blurred06.02.06.007; 17.17.01.010--
Vomiting07.01.07.003--
Erectile dysfunction19.08.04.001; 21.03.01.007--
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