Drug Name |
Proguanil |
Drug ID |
BADD_D01853 |
Description |
Proguanil is a prophylactic antimalarial drug, which works by stopping the malaria parasite, _Plasmodium falciparum_ and _Plasmodium vivax_, from reproducing once it is in the red blood cells. It does this by inhibiting the enzyme, dihydrofolate reductase, which is involved in the reproduction of the parasite. |
Indications and Usage |
For the causal prevention and suppression of malaria caused by susceptible strains of P. falciparum and other species of Plasmodium found in some geographical areas of the world. |
Marketing Status |
approved |
ATC Code |
P01BB01 |
DrugBank ID |
DB01131
|
KEGG ID |
D08428
|
MeSH ID |
D002727
|
PubChem ID |
6178111
|
TTD Drug ID |
D0P8RS
|
NDC Product Code |
65977-0071 |
UNII |
S61K3P7B2V
|
Synonyms |
Proguanil | Chlorguanid | Chloroguanide | Proguanil Hydrochloride | Hydrochloride, Proguanil | Chloroguanide Hydrochloride | Hydrochloride, Chloroguanide | Paludrine | Paludrin | Bigumal | Chloriguane |