Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Procaine hydrochloride
Drug ID BADD_D01845
Description A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in treatment-experienced HIV patients [L1215].
Indications and Usage Used as a local anesthetic primarily in oral surgery
Marketing Status approved; investigational; vet_approved
ATC Code N01BA02; C05AD05; S01HA05
DrugBank ID DB00721
KEGG ID D00740
MeSH ID D011343
PubChem ID 5795
TTD Drug ID D0TZ1G
NDC Product Code 81999-0004; 20362-0585; 51552-0505
UNII 95URV01IDQ
Synonyms Procaine | Gerokit | Novocain | Novocaine | Procain Braun | Procain curasan | Procain Rödler | Procain Jenapharm | Procain Steigerwald | procain-loges | Procaina Serra | Procaine Hydrochloride | Hydrochloride, Procaine | Pröcaine chlorhydrate Lavoisier | Röwo Procain | Anuject | Geriocaine | Hewedolor-Procain | Lophakomp-Procain N
Chemical Information
Molecular Formula C13H21ClN2O2
CAS Registry Number 51-05-8
SMILES CCN(CC)CCOC(=O)C1=CC=C(C=C1)N.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Arachnoiditis12.02.04.002; 17.06.01.001--
Bradycardia02.03.02.002---
Cardiac arrest02.03.04.001--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Hypertension24.08.02.001--
Hypotension24.06.03.002--
Meningism17.02.05.007--
Nausea07.01.07.001--
Nervousness19.06.02.003---
Oedema08.01.07.006; 14.05.06.010---
Respiratory disorder22.02.07.002---
Skin lesion23.03.03.010---
Tremor17.01.06.002--
Urticaria10.01.06.001; 23.04.02.001--
Vision blurred06.02.06.007; 17.17.01.010--
Vomiting07.01.07.003--
Spinal cord paralysis17.01.04.009---
Post lumbar puncture syndrome12.02.04.004; 17.14.01.012---
Cranial nerve disorder17.04.01.001---
Myocardial depression02.04.02.015---
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