Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Prednisone
Drug ID BADD_D01834
Description A synthetic anti-inflammatory glucocorticoid derived from [cortisone].[A187463] It is biologically inert and converted to [prednisolone] in the liver.[L10502] Prednisone was granted FDA approval on 21 February 1955.[L10496]
Indications and Usage Prednisone is indicated as an anti-inflammatory or immunosuppressive drug for allergic, dermatologic, gastrointestinal, hematologic, ophthalmologic, nervous system, renal, respiratory, rheumatologic, infectious, endocrine, or neoplastic conditions as well as in organ transplant.[L10502]
Marketing Status approved; vet_approved
ATC Code A07EA03; H02AB07
DrugBank ID DB00635
KEGG ID D00473
MeSH ID D011241
PubChem ID 5865
TTD Drug ID D0IL7L
NDC Product Code 80425-0068; 82982-041; 0591-5052; 42291-727; 42708-105; 43063-911; 50090-0439; 50090-3361; 51655-242; 53002-0610; 55154-4950; 58118-0173; 59746-175; 60219-1707; 61919-321; 62135-471; 63187-066; 63629-2255; 63629-2263; 0378-0642; 64380-949; 67296-0138; 67296-1194; 67296-1755; 68071-2304; 68071-5242; 70518-0632; 70518-2115; 70518-2138; 71205-729; 71205-755; 71205-818; 0054-4741; 71335-1926; 0591-5443; 71335-2153; 0603-5336; 76420-068; 80425-0069; 82982-042; 10135-777; 10135-779; 50090-3137; 51655-493; 51655-763; 51655-765; 51655-779; 55154-4938; 59746-171; 60760-932; 63187-807; 63629-2254; 63629-2434; 64380-835; 66267-173; 66267-860; 67296-1444; 68071-2661; 68071-4691; 68071-5195; 68788-7372; 68788-7692; 68788-8166; 68788-9551; 70518-2675; 70518-2704; 70518-3540; 70934-880; 70954-060; 71205-741; 71335-2088; 0054-8739; 72162-1169; 72189-275; 0615-8438; 80425-0105; 64958-0002; 43063-968; 50090-6225; 51655-410; 51655-988; 53002-3090; 54348-506; 55154-4946; 55289-330; 55700-208; 60219-1705; 61919-235; 61919-365; 63629-7917; 67296-0140; 0054-0019; 68788-8212; 70954-061; 71205-089; 71335-1780; 71335-2149; 0054-8724; 0054-8740; 0054-9828; 72162-1170; 0615-8307; 0615-8441; 59651-489; 60760-002; 63629-2256; 64380-782; 67296-1183; 0054-0018; 70518-1553; 70518-2916; 70934-095; 70954-057; 71205-460; 71205-797; 71335-2122; 71335-2134; 0603-5337; 71610-721; 0054-9818; 0615-8306; 72189-489; 0615-8439; 80425-0106; 0904-6923; 13672-033; 10135-778; 43063-703; 45865-670; 53002-3252; 59746-172; 60687-145; 60760-255; 60760-790; 61919-108; 63187-085; 63629-2258; 63629-2435; 0378-0641; 68071-2209; 68071-2578; 68071-3143; 68788-6440; 68788-7752; 68788-8267; 70954-059; 71205-537; 71335-1524; 71335-1628; 71335-1736; 71335-1737; 71335-2051; 0603-5335; 0603-5339; 0615-8440; 75987-021; 75987-022; 0591-5442; 13672-032; 42708-115; 50090-3336; 51655-355; 51655-416; 51655-935; 51655-972; 59651-487; 60219-1708; 62135-470; 63187-300; 63187-997; 63629-2260; 63629-2262; 68071-1779; 68788-8116; 0527-2934; 70518-0305; 70518-0306; 70518-1120; 70882-117; 0054-4742; 71335-1516; 71335-1525; 0603-5338; 76420-067; 13672-031; 51552-0028; 10135-774; 42708-136; 50090-6123; 50090-6259; 51655-068; 51655-359; 51655-701; 53002-3091; 53002-3520; 59651-488; 60687-122; 63187-243; 63629-1579; 63629-2261; 0378-0640; 64380-784; 64380-785; 67296-0247; 67296-1065; 67296-1455; 67296-1457; 68071-2696; 68071-5196; 68071-5233; 0527-2933; 70518-1561; 70518-2676; 70518-3138; 71205-403; 71335-0464; 0615-8395; 72789-235; 0904-7127; 42708-167; 50090-3330; 50090-3354; 50090-5816; 51407-356; 51407-360; 51655-726; 55154-4949; 59651-484; 60760-715; 63629-2257; 68071-2781; 68788-8184; 0527-2930; 70518-0307; 70518-2555; 70518-3142; 70934-096; 70954-056; 71205-407; 71335-0623; 0054-4728; 0054-9817; 72162-1171; 75987-020; 10135-776; 60722-1002; 82298-103; 42291-771; 42708-114; 42708-166; 51655-349; 51655-760; 59651-486; 59746-173; 60219-1706; 60760-615; 63187-037; 67296-1083; 67296-1446; 67544-399; 0054-0017; 70518-3537; 70934-291; 0054-3722; 71205-362; 71335-0335; 71335-0508; 71335-2079; 71610-641; 72162-1172; 72189-246; 80425-0193; 38779-0154; 57582-003; 42708-045; 43063-866; 50090-6122; 51407-355; 51407-357; 51655-197; 51655-541; 51655-716; 53002-3250; 55700-203; 55700-209; 60687-134; 61919-326; 63187-020; 63629-1605; 63629-2259; 63629-2264; 63739-588; 64380-783; 67296-1203; 67296-1767; 67296-1886; 68071-2771; 70518-2314; 70518-2703; 70518-3401; 70518-3476; 70518-3539; 70518-3555; 70954-058; 71205-239; 71205-421; 71205-665; 71335-1915; 71335-2069; 71335-2160; 71335-9715; 72189-430; 0615-8391; 76420-069; 49452-6000; 10135-775; 42291-770; 42291-783; 50090-4785; 50090-5814; 50090-6376; 51407-358; 51407-359; 51655-208; 51655-939; 55154-3564; 58118-5442; 59651-485
UNII VB0R961HZT
Synonyms Prednisone | Dehydrocortisone | delta-Cortisone | Rectodelt | Prednison Hexal | Sterapred | Ultracorten | Winpred | Apo-Prednisone | Cortan | Cortancyl | Panafcort | Cutason | Decortin | Dacortin | Decortisyl | Deltasone | Encortone | Encorton | Enkortolon | Kortancyl | Liquid Pred | Meticorten | Orasone | Panasol | Predni Tablinen | Prednidib | Predniment | Prednison Acsis | Acsis, Prednison | Pronisone | Sone | Prednison Galen
Chemical Information
Molecular Formula C21H26O5
CAS Registry Number 53-03-2
SMILES CC12CC(=O)C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Gastritis07.08.02.0010.000051%
Gastritis erosive07.04.03.0030.000009%-
Gastrointestinal fistula07.11.05.0010.000013%
Gastrooesophageal reflux disease07.02.02.003--
Gastrointestinal carcinoma07.21.03.001; 16.13.04.001---
Gastrointestinal disorder07.11.01.0010.000265%-
Gastrointestinal haemorrhage07.12.02.001; 24.07.02.0090.000226%-
Gastrointestinal necrosis07.15.01.003; 24.04.08.0060.000018%
Gastrointestinal pain07.01.05.0050.000057%
Gastrointestinal perforation07.04.04.0010.000031%-
Gastrointestinal stenosis07.13.01.007---
Generalised anxiety disorder19.06.01.0040.000009%-
Generalised oedema08.01.07.004; 14.05.06.0070.000031%
Generalised tonic-clonic seizure17.12.01.0020.000054%-
Genital ulceration21.10.05.001; 23.07.03.004---
Gestational diabetes05.06.01.008; 14.06.01.008; 18.02.04.0010.000018%-
Gingival bleeding07.09.07.001; 24.07.02.0100.000018%-
Gingival disorder07.09.13.004---
Gingival pain07.09.13.0100.000018%
Gingival swelling07.09.13.013---
Glaucoma06.03.01.0020.000051%
Glomerulonephritis10.02.01.006; 20.05.01.0010.000018%-
Glossodynia07.14.02.0010.000022%-
Glucose tolerance decreased13.02.02.004---
Glucose tolerance impaired05.06.02.001; 14.06.02.0010.000022%
Glycosuria20.02.01.005--
Gout14.09.01.001; 15.01.06.0010.000022%-
Graft versus host disease10.02.01.027; 12.02.09.0010.000036%-
Granuloma08.01.05.001; 23.03.15.0010.000009%-
Guillain-Barre syndrome10.04.10.005; 11.07.01.001; 17.09.01.0010.000031%
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