Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Prednisolone
Drug ID BADD_D01831
Description Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.[A187463] Prednisolone was granted FDA approval on 21 June 1955.[L9431]
Indications and Usage Prednisolone is indicated to treat endocrine, rheumatic, and hematologic disorders; collagen, dermatologic, ophthalmic, respiratory, and gastrointestinal diseases; allergic and edematous states; and other conditions like tuberculous meningitis.[L9542]
Marketing Status approved; vet_approved
ATC Code A01AC04; A07EA01; C05AA04; D07AA03; D07XA02; H02AB06; R01AD02; S01BA04; S01CB02; S02BA03; S03BA02
DrugBank ID DB00860
KEGG ID D00472
MeSH ID D011239
PubChem ID 5755
TTD Drug ID D0D1SG
NDC Product Code 38779-0150; 64958-0097; 82298-104; 67296-1656; 50383-042; 59651-491; 63187-466; 0527-5406; 65089-0038; 50090-0655; 57582-004; 62135-437; 73534-505; 49452-5980; 82298-105; 82298-106; 60592-911; 60722-3001; 51927-0234; 22552-0052
UNII 9PHQ9Y1OLM
Synonyms Prednisolone | Predate | Predonine | Di-Adreson-F | Di Adreson F | DiAdresonF
Chemical Information
Molecular Formula C21H28O5
CAS Registry Number 50-24-8
SMILES CC12CC(C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Drug resistance08.06.01.0050.000332%-
Induration08.01.03.0200.000035%-
Neurological symptom17.02.05.0100.000052%-
Skin test negative13.06.04.002---
Trigeminal nerve disorder17.04.08.0040.000035%
Biliary tract disorder09.02.03.0010.000035%-
Brain neoplasm16.30.01.003; 17.20.01.0030.000035%-
Connective tissue disorder10.04.04.026; 15.06.01.0060.000052%-
Eye movement disorder06.05.02.008; 17.02.05.0250.000035%-
Eyelid disorder06.08.03.010; 23.03.03.0280.000035%-
Finger deformity15.10.03.0030.000035%-
Embolism24.01.01.009--
Gastrointestinal motility disorder07.02.03.0010.000052%-
Haematotoxicity01.05.01.007; 12.03.01.0250.000052%-
Infarction24.04.02.0170.000105%-
Inflammation08.01.05.007; 10.02.01.0890.000322%-
Lymphoproliferative disorder01.13.02.001; 16.21.02.0010.000140%-
Malnutrition14.03.02.0040.000052%-
Metastatic neoplasm16.16.01.0070.000035%-
Motor dysfunction15.05.06.006; 17.01.02.0310.000035%-
Mucosal erosion08.01.06.0090.000035%-
Mucosal haemorrhage08.01.06.005; 24.07.01.0110.000035%-
Soft tissue disorder15.03.02.0120.000035%
Spinal cord disorder17.10.01.0100.000052%-
Spondylitis15.01.09.0020.000070%-
Venous thrombosis limb24.01.02.0090.000105%-
Corneal disorder06.08.01.0040.000077%-
Psychiatric symptom19.01.02.0010.000070%-
Ill-defined disorder08.01.03.049---
Intervertebral disc disorder15.10.01.0030.000052%-
The 26th Page    First    Pre   26 27 28 29 30    Next   Last    Total 36 Pages
ADReCS-Target
Drug Name ADR Term Target
Tip:  Drug Name  ADR Term  Protein  Variation  Gene