Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Prednisolone
Drug ID BADD_D01831
Description Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.[A187463] Prednisolone was granted FDA approval on 21 June 1955.[L9431]
Indications and Usage Prednisolone is indicated to treat endocrine, rheumatic, and hematologic disorders; collagen, dermatologic, ophthalmic, respiratory, and gastrointestinal diseases; allergic and edematous states; and other conditions like tuberculous meningitis.[L9542]
Marketing Status approved; vet_approved
ATC Code A01AC04; A07EA01; C05AA04; D07AA03; D07XA02; H02AB06; R01AD02; S01BA04; S01CB02; S02BA03; S03BA02
DrugBank ID DB00860
KEGG ID D00472
MeSH ID D011239
PubChem ID 5755
TTD Drug ID D0D1SG
NDC Product Code 38779-0150; 64958-0097; 82298-104; 67296-1656; 50383-042; 59651-491; 63187-466; 0527-5406; 65089-0038; 50090-0655; 57582-004; 62135-437; 73534-505; 49452-5980; 82298-105; 82298-106; 60592-911; 60722-3001; 51927-0234; 22552-0052
UNII 9PHQ9Y1OLM
Synonyms Prednisolone | Predate | Predonine | Di-Adreson-F | Di Adreson F | DiAdresonF
Chemical Information
Molecular Formula C21H28O5
CAS Registry Number 50-24-8
SMILES CC12CC(C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Skin hyperpigmentation23.05.01.0030.000035%
Skin lesion23.03.03.0100.000175%-
Skin necrosis23.03.03.0110.000122%-
Skin odour abnormal23.03.03.0120.000070%
Skin papilloma11.05.07.001; 16.26.01.002; 23.10.01.0020.000052%
Skin reaction10.01.03.019; 23.03.03.0130.000070%-
Skin striae23.01.05.0020.000070%-
Skin ulcer23.07.03.003; 24.04.03.0070.000357%
Sleep disorder19.02.04.0010.000332%-
Small intestinal perforation07.04.06.0060.000122%
Sodium retention14.05.04.003---
Speech disorder17.02.08.003; 19.19.02.002; 22.12.03.0270.000245%-
Spinal compression fracture12.04.04.001; 14.04.04.003; 15.08.05.004---
Spinal cord compression17.10.01.0060.000035%
Spinal osteoarthritis15.01.04.0030.000052%-
Splenic infarction01.09.02.004; 24.04.08.0240.000052%-
Splenomegaly01.09.02.0010.000087%-
Sputum discoloured22.02.03.0100.000035%-
Squamous cell carcinoma16.16.01.0020.000140%-
Squamous cell carcinoma of skin16.03.02.005; 23.08.02.0050.000070%-
Steroid withdrawal syndrome05.01.02.007; 08.06.02.013; 19.04.02.0140.000332%-
Stevens-Johnson syndrome10.01.01.045; 11.07.01.005; 12.03.01.014; 23.03.01.0070.000157%
Stillbirth08.04.01.006; 18.01.02.0020.000105%-
Stress19.06.02.004---
Stress ulcer07.04.04.0070.000035%-
Stridor22.04.02.0030.000052%
Subcutaneous emphysema12.02.06.002; 23.07.04.0060.000087%
Sudden death02.03.04.013; 08.04.01.0030.000087%
Superior sagittal sinus thrombosis17.08.03.001; 24.01.04.0040.000087%-
Supraventricular tachycardia02.03.03.0120.000070%
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ADReCS-Target
Drug Name ADR Term Target
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