| Pharmaceutical Information |
| Drug Name |
Prazosin hydrochloride |
| Drug ID |
BADD_D01828 |
| Description |
Prazosin, also known as _Minipress_, is a drug used to treat hypertension. Prazosin is marketed by _Pfizer_ and was initially approved by the FDA in 1988 [L5828]. It belongs to the class of drugs known as alpha-1 antagonists [FDA label], [A176630].
Recently, many studies have evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress disorder (PTSD) and associated nightmares [A176618, A176621, A176624]. |
| Indications and Usage |
This drug is indicated for the treatment of hypertension (high blood pressure). Prazosin can be given alone or given with other blood pressure-lowering drugs, including diuretics or beta-adrenergic blocking agents [FDA label].
Prazosin does not negatively impact lung function, and therefore may be used to manage hypertension in patients who are asthmatic or patients with chronic obstructive lung disease (COPD)[A176630]. |
| Marketing Status |
approved |
| ATC Code |
C02CA01 |
| DrugBank ID |
DB00457
|
| KEGG ID |
D00609
|
| MeSH ID |
D011224
|
| PubChem ID |
68546
|
| TTD Drug ID |
D0WV3U
|
| NDC Product Code |
0069-4270; 58159-043; 0093-4069; 62332-693; 66993-431; 68788-7335; 68788-7824; 70010-086; 70518-1476; 70518-2177; 70518-2178; 71335-9648; 71610-694; 76282-722; 0378-1101; 51079-630; 62559-581; 63629-8325; 68071-2914; 70010-085; 70518-3669; 70518-3679; 70954-021; 71335-1724; 71335-1932; 0904-7020; 43063-260; 46708-692; 51079-632; 63629-8750; 70377-067; 70518-3375; 71610-693; 59762-5350; 68084-996; 70010-084; 70518-0241; 70518-1443; 70518-3186; 70518-3271; 70518-3352; 70518-3383; 70756-430; 71335-2042; 76282-723; 50923-0462; 51927-5040; 50090-5697; 60429-973; 60687-572; 62559-580; 63629-8756; 66993-433; 68071-2972; 70518-1884; 70518-2705; 70954-020; 71610-046; 0069-4260; 0904-7021; 10135-668; 0069-4380; 46708-691; 50090-5695; 68071-2951; 68788-8067; 70518-1895; 70518-2065; 70756-440; 10135-667; 58343-0140; 62207-974; 0069-4310; 55289-536; 59762-5310; 62332-691; 66993-432; 68788-7849; 68788-8144; 70954-019; 71205-585; 76282-721; 50379-0019; 50090-2845; 59651-272; 59762-5320; 60429-971; 0378-2302; 0378-3205; 68071-2713; 70377-066; 70377-068; 46708-693; 51079-631; 55154-4156; 59651-271; 59651-273; 62332-692; 70518-1756; 70756-429; 71335-1401; 10135-666; 60715-0011; 0069-4370; 60429-972; 68071-2993; 68084-997; 71335-1085; 71610-571; 0904-7022; 63809-2742; 0093-4067; 0093-4068; 43063-248; 55154-8181; 55700-492 |
| UNII |
X0Z7454B90
|
| Synonyms |
Prazosin | Furazosin | Prazosin Hydrochloride | Hydrochloride, Prazosin | Prazosin HCL | HCL, Prazosin | Minipress | Pratsiol |
|
| Chemical Information |
| Molecular Formula |
C19H22ClN5O4 |
| CAS Registry Number |
19237-84-4 |
| SMILES |
COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4=CC=CO4)N)OC.Cl |
| Chemical Structure |
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| ADRs Induced by Drug |
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