Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Potassium bicarbonate
Drug ID BADD_D01807
Description Potassium bicarbonate is a white, crystalline, slightly alkaline and salty substance. It is produced by the passage of carbon dioxide through an aqueous potassium carbonate solution. It is used in medicine as an antacid.[T141] It is registered in the FDA under the section of suitable, safe and effective ingredients for OTC antacids.[L1836] This FDA denomination classifies potassium bicarbonate as a GRAS ingredient.[L1837]
Indications and Usage Potassium bicarbonate is used as an antacid, electrolyte replenisher and potassium supplement. It can also be used as an excipient in drug formulations.[L1837] An antacid is a medication used to neutralize gastric acid in a short timeframe after ingestion and the effect is soon overcome by meal-stimulated acid secretion.[A32214]
Marketing Status approved
ATC Code Not Available
DrugBank ID DB11098
KEGG ID D02077
MeSH ID C026329
PubChem ID 516893
TTD Drug ID Not Available
NDC Product Code 51801-011; 51801-012; 51801-013; 51801-014; 51801-005; 51801-007; 51801-001; 0245-5326; 51801-006
UNII HM5Z15LEBN
Synonyms potassium bicarbonate | potassium hydrocarbonate | KHCO3
Chemical Information
Molecular Formula KHCO3
CAS Registry Number 298-14-6
SMILES C(=O)(O)[O-].[K+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001---
Asthenia08.01.01.001---
Asthma10.01.03.010; 22.03.01.002---
Choking22.12.03.003---
Chronic obstructive pulmonary disease22.03.01.007---
Condition aggravated08.01.03.004---
Cough22.02.03.001--
Diabetes mellitus05.06.01.001; 14.06.01.001---
Diarrhoea07.02.01.001--
Drug dependence19.07.06.011---
Dyspnoea02.11.05.003; 22.02.01.004--
Haematemesis07.12.02.002; 24.07.02.011---
Hallucination19.10.04.003--
Hyperkalaemia14.05.03.001--
Hypertension24.08.02.001--
Loss of consciousness17.02.04.004---
Lung disorder22.02.07.001---
Malaise08.01.01.003--
Myocardial infarction02.02.02.007; 24.04.04.009--
Nausea07.01.07.001--
Therapeutic response unexpected08.06.01.001---
Thyroid disorder05.02.01.002---
Visual impairment06.02.10.013---
Vomiting07.01.07.003--
Fibromyalgia15.05.02.002---
Hypoacusis04.02.01.006--
Disease recurrence08.01.03.050---
Type 2 diabetes mellitus05.06.01.003; 14.06.01.003---
Coeliac disease07.17.01.008; 10.04.04.012; 14.02.01.007---
Illness08.01.03.091---
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