Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pomalidomide
Drug ID BADD_D01798
Description Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.
Indications and Usage Pomalidomide is indicated for patients with multiple myeloma who have received at least two prior therapies including lenalidomide and bortezomib and have demonstrated disease progression on or within 60 days of completion of the last therapy.
Marketing Status approved
ATC Code L04AX06
DrugBank ID DB08910
KEGG ID D08976
MeSH ID C467566
PubChem ID 134780
TTD Drug ID D0A3ZU
NDC Product Code 65015-893; 17337-0068; 63069-404; 68554-0092; 70225-1106; 59572-501; 59572-502; 55111-989; 68554-0091; 82245-0108; 63069-402; 42973-232; 54893-0038; 59572-503; 59572-504; 63069-403
UNII D2UX06XLB5
Synonyms pomalidomide | CC-4047 | CC 4047 | CC4047 | Imnovid | Pomalyst | actimid
Chemical Information
Molecular Formula C13H11N3O4
CAS Registry Number 19171-19-8
SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Skin texture abnormal23.03.03.0680.000820%-
End stage renal disease20.01.03.0190.001206%-
Intracranial mass17.11.01.0170.000482%-
Tongue discomfort07.14.02.0190.001760%-
Biliary obstruction09.02.02.0050.000362%-
Breast discolouration21.05.05.016; 23.03.03.0730.000940%-
Colorectal adenoma07.20.01.019; 16.05.02.0090.000241%-
Disease complication08.01.03.0870.003665%-
Gait inability08.01.02.011; 17.02.05.0690.010898%-
Hyperaesthesia teeth07.09.06.0050.000940%-
Illness08.01.03.0910.052900%-
Limb mass15.03.05.0190.000940%-
Periorbital swelling06.08.03.032; 10.01.05.025; 23.04.01.0250.001230%-
Physical deconditioning08.01.03.0960.000723%-
Plasma cell myeloma in remission01.14.02.007; 16.23.02.0070.000820%-
Product intolerance08.06.01.0450.000820%-
Pulmonary amyloidosis10.02.05.010; 22.01.02.0340.000241%-
Sensitive skin23.03.03.0970.003689%-
Signet-ring cell carcinoma16.16.01.0230.000241%-
Sinus pain22.12.03.0230.000530%
Skin cancer metastatic16.03.02.013; 23.08.02.0130.000241%-
Superficial vein thrombosis24.01.02.0160.001133%-
Swelling of eyelid06.04.04.018; 10.01.05.026; 23.04.01.0260.001061%-
Taste disorder07.14.03.004; 17.02.07.0290.013189%-
Vertebral column mass15.02.04.0480.000241%-
The 16th Page    First    Pre   16    Total 16 Pages