Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Piperacillin sodium
Drug ID BADD_D01780
Description Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Indications and Usage For the treatment of polymicrobial infections.
Marketing Status approved
ATC Code J01CA12
DrugBank ID DB00319
KEGG ID D00466
MeSH ID D010878
PubChem ID 23666879
TTD Drug ID D04ZAH
NDC Product Code 72977-0002; 65862-277; 50915-118; 66721-300
UNII M98T69Q7HP
Synonyms Piperacillin | Pipercillin | Piperacillin Sodium | Sodium, Piperacillin | Piperacillin Monosodium Salt | Monosodium Salt, Piperacillin | Salt, Piperacillin Monosodium | Pipracil | Pipril | T1220 | T-1220 | T 1220 | Piperacillin-Ratiopharm | Piperacillin Ratiopharm | Pipera-Hameln | Pipera Hameln | AB-Piperacillin | AB Piperacillin | Piperacillin Curasan | Curasan, Piperacillin | Piperacillin Fresenius | Piperacillin Hexal | Cl-227193 | Cl 227193 | Cl227193 | Pipcil
Chemical Information
Molecular Formula C23H26N5NaO7S
CAS Registry Number 59703-84-3
SMILES CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].[Na +]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agranulocytosis01.02.03.001---
Alanine aminotransferase increased13.03.04.005--
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Aspartate aminotransferase increased13.03.04.011--
Bleeding time prolonged13.01.02.002---
Blood creatinine increased13.13.01.004--
Blood lactate dehydrogenase increased13.04.02.002--
Blood potassium decreased13.11.01.010---
Diarrhoea07.02.01.001--
Diarrhoea haemorrhagic07.02.01.002; 24.07.02.004---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Ecchymosis01.01.03.001; 23.06.01.001; 24.07.06.002---
Eosinophilia01.02.04.001--
Erythema23.03.06.001---
Erythema multiforme10.01.03.015; 23.03.01.003--
Fatigue08.01.01.002--
Haematoma24.07.01.001--
Haemolytic anaemia01.06.03.002---
Headache17.14.01.001--
Hepatitis cholestatic09.01.01.002---
Hyperbilirubinaemia01.06.04.003; 09.01.01.003; 14.11.01.010---
Hypokalaemia14.05.03.002--
Hypotonia15.05.04.008; 17.05.02.002---
Leukopenia01.02.02.001---
Nausea07.01.07.001--
Neutropenia01.02.03.004---
Pain08.01.08.004--
Pancytopenia01.03.03.003---
Pruritus23.03.12.001--
Pseudomembranous colitis07.19.01.003; 11.02.02.002---
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