ADReCS

Pharmaceutical Information

Drug Name	Piperacillin
Drug ID	BADD_D01779
Description	Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Indications and Usage	For the treatment of polymicrobial infections.
Marketing Status	approved
ATC Code	J01CA12
DrugBank ID	DB00319
KEGG ID	D02251; D08380
MeSH ID	D010878
PubChem ID	43672
TTD Drug ID	D04ZAH
NDC Product Code	72977-0002; 65862-277; 50915-118; 66721-300
UNII	X00B0D5O0E
Synonyms	Piperacillin \| Pipercillin \| Piperacillin Sodium \| Sodium, Piperacillin \| Piperacillin Monosodium Salt \| Monosodium Salt, Piperacillin \| Salt, Piperacillin Monosodium \| Pipracil \| Pipril \| T1220 \| T-1220 \| T 1220 \| Piperacillin-Ratiopharm \| Piperacillin Ratiopharm \| Pipera-Hameln \| Pipera Hameln \| AB-Piperacillin \| AB Piperacillin \| Piperacillin Curasan \| Curasan, Piperacillin \| Piperacillin Fresenius \| Piperacillin Hexal \| Cl-227193 \| Cl 227193 \| Cl227193 \| Pipcil

Chemical Information

Molecular Formula	C23H27N5O7S
CAS Registry Number	61477-96-1
SMILES	CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)O
Chemical Structure

ADRs Induced by Drug

*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.

ADR Term	ADReCS ID	ADR Frequency (FAERS)	ADR Severity Grade (FAERS)	ADR Severity Grade (CTCAE)
Abdominal pain	07.01.05.002	-	-
Activated partial thromboplastin time prolonged	13.01.02.001	-	-
Agranulocytosis	01.02.03.001	-	-	-
Alanine aminotransferase increased	13.03.04.005	-	-
Anaemia	01.03.02.001	-	-
Anaphylactic shock	10.01.07.002; 24.06.02.004	-	-	-
Anaphylactoid reaction	10.01.07.003; 24.06.03.007	-	-	-
Arthralgia	15.01.02.001	-	-
Aspartate aminotransferase increased	13.03.04.011	-	-
Asthenia	08.01.01.001	-	-	-
Bleeding time prolonged	13.01.02.002	-	-	-
Blood albumin decreased	13.09.01.001	-	-	-
Blood bilirubin increased	13.03.04.018	-	-
Blood creatinine increased	13.13.01.004	-	-
Blood glucose decreased	13.02.02.001	-	-	-
Blood potassium decreased	13.11.01.010	-	-	-
Blood urea increased	13.13.01.006	-	-	-
Body temperature increased	13.15.01.001	-	-	-
Bone disorder	15.02.04.004	-	-	-
Chills	08.01.09.001; 15.05.03.016	-	-
Constipation	07.02.02.001	-	-
Coombs direct test positive	13.01.01.001	-	-	-
Dermatitis	23.03.04.002	-	-	-
Dermatitis bullous	23.03.01.002	-	-
Diarrhoea	07.02.01.001	-	-
Diarrhoea haemorrhagic	07.02.01.002; 24.07.02.004	-	-	-
Dizziness	02.11.04.006; 17.02.05.003; 24.06.02.007	-	-
Drug interaction	08.06.03.001	-	-	-
Dry mouth	07.06.01.002	-	-
Dyspepsia	07.01.02.001	-	-

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