| Drug Name |
Phenylephrine hydrochloride |
| Drug ID |
BADD_D01763 |
| Description |
Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and induce local vasoconstriction.[A187370] The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s.[A187376]
Phenylephrine was granted FDA approval in 1939.[L9413] |
| Indications and Usage |
Phenylephrine injections are indicated to treat hypotension caused by shock or anesthesia,[L9416, L9410] an ophthalmic formulation is indicated to dilate pupils[L9413] and induce vasoconstriction, an intranasal formulation is used to treat congestion, and a topical formulation is used to treat hemorrhoids.[A187370] Off-label uses include situations that require local blood flow restriction such as the treatment of priapism.[A187370] |
| Marketing Status |
approved |
| ATC Code |
S01GA05; C01CA06; R01AA04; R01AB01; R01BA03; S01FB01 |
| DrugBank ID |
DB00388
|
| KEGG ID |
D00511
|
| MeSH ID |
D010656
|
| PubChem ID |
5284443
|
| TTD Drug ID |
D0O6IU
|
| NDC Product Code |
0641-6142; 0641-6229; 0904-6753; 12538-0103; 62991-2046; 0113-0648; 41163-648; 41250-648; 41520-094; 42023-214; 47682-017; 47682-162; 50580-437; 51662-1576; 55150-301; 55910-802; 56062-094; 58809-940; 61990-0213; 68083-339; 68083-465; 68210-4196; 71288-807; 0781-3466; 81284-212; 81522-648; 12538-0104; 14037-9999; 62579-550; 16729-466; 0113-0094; 36800-648; 42702-103; 46122-149; 50580-784; 53943-131; 0363-0390; 61990-0211; 63941-331; 70069-813; 70756-621; 11822-0990; 16729-465; 41415-728; 55154-8226; 55910-276; 68998-231; 70121-1577; 0573-1378; 71288-808; 71839-127; 71872-7043; 71872-7159; 72572-570; 55150-300; 55150-302; 62011-0085; 63029-401; 63323-751; 63868-697; 68210-4172; 68998-131; 70000-0506; 70069-801; 70756-614; 70756-629; 0641-6189; 73598-1262; 0781-3422; 81284-211; 81522-094; 0395-8122; 53592-221; 17478-206; 24385-390; 47682-990; 0225-0810; 55910-094; 62011-0077; 68210-4224; 68210-5011; 69842-443; 70069-811; 70069-812; 70121-1578; 72036-131; 72288-648; 0781-3458; 0781-9226; 0781-9227; 38779-0247; 21130-728; 36800-094; 41520-831; 43598-172; 49035-648; 51754-4020; 57344-131; 61990-0212; 0363-0648; 63029-403; 65145-117; 0404-9931; 69790-161; 70069-802; 70756-623; 71839-128; 0067-2086; 51927-1225; 16729-464; 23155-620; 25021-315; 41520-729; 0225-0805; 0363-2023; 65145-116; 68083-338; 68210-4234; 69842-648; 70594-065; 71872-7267; 72485-505; 0641-6245; 73598-1264; 82501-1577; 62331-028; 64431-0001; 68210-1210; 17478-201; 24385-603; 43598-199; 47682-161; 49348-700; 0225-0800; 65145-115; 70594-064; 70756-649; 71839-129; 72485-504; 0641-6188; 0641-6246; 81284-213; 49452-5291; 51927-0239; 57218-810; 58747-0502; 11673-204; 30142-539; 37808-531; 37808-728; 42023-215; 47682-809; 49348-197; 59779-390; 0363-0717; 70000-0132; 70069-803; 70594-063; 70756-622; 71863-208; 71872-7231; 71872-7273; 72485-506; 72572-571; 54871-0092; 0113-7094; 41250-231; 46122-689; 49035-131; 51754-4000; 55670-163; 70121-1579; 71863-202; 72288-094; 73408-990; 0781-9228; 51552-0232; 62579-546; 0113-2004; 36800-631; 37808-209; 51754-4010; 59779-838 |
| UNII |
04JA59TNSJ
|
| Synonyms |
Phenylephrine | (R)-3-Hydroxy-alpha-((methylamino)methyl)benzenemethanol | Metasympatol | Mezaton | Phenylephrine Hydrochloride | Phenylephrine Tannate | Tannate, Phenylephrine | Metaoxedrin | Neo-Synephrine | Neo Synephrine | Neosynephrine |
