Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Phenoxybenzamine hydrochloride
Drug ID BADD_D01755
Description An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Indications and Usage For the treatment of phaeochromocytoma (malignant), benign prostatic hypertrophy and malignant essential hypertension.
Marketing Status approved
ATC Code C04AX02
DrugBank ID DB00925
KEGG ID D00507
MeSH ID D010643
PubChem ID 5284441
TTD Drug ID D0X2DK
NDC Product Code 43744-458; 66993-066; 58159-044; 59651-327; 59212-001; 70954-365; 14096-114; 58032-1014; 59981-023; 47621-309; 60219-1502; 49884-038; 76438-003; 76339-143; 0054-0349; 51927-0261; 59651-298
UNII X1IEG24OHL
Synonyms Phenoxybenzamine | Phenoxybenzamine Hydrochloride | Hydrochloride, Phenoxybenzamine | Dibenzyline | Dibenzylin | Dibenyline | Dibenylene | Dibenziran | Dibenzyran
Chemical Information
Molecular Formula C18H22ClNO.ClH
CAS Registry Number 63-92-3
SMILES CC(COC1=CC=CC=C1)N(CCCl)CC2=CC=CC=C2.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Ejaculation delayed21.03.01.001---
Fatigue08.01.01.002--
Miosis06.05.03.003; 17.02.11.002---
Nasal congestion22.04.04.001--
Orthostatic hypotension17.05.01.020; 24.06.03.004---
Somnolence17.02.04.006; 19.02.05.003--
Tachycardia02.03.02.007---
Gastrointestinal tract irritation07.08.03.008---
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