Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Phenoxybenzamine
Drug ID BADD_D01754
Description An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Indications and Usage For the treatment of phaeochromocytoma (malignant), benign prostatic hypertrophy and malignant essential hypertension.
Marketing Status approved
ATC Code C04AX02
DrugBank ID DB00925
KEGG ID D08358
MeSH ID D010643
PubChem ID 4768
TTD Drug ID D0X2DK
NDC Product Code 69988-0016
UNII 0TTZ664R7Z
Synonyms Phenoxybenzamine | Phenoxybenzamine Hydrochloride | Hydrochloride, Phenoxybenzamine | Dibenzyline | Dibenzylin | Dibenyline | Dibenylene | Dibenziran | Dibenzyran
Chemical Information
Molecular Formula C18H22ClNO
CAS Registry Number 59-96-1
SMILES CC(COC1=CC=CC=C1)N(CCCl)CC2=CC=CC=C2
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001---
Asthenia08.01.01.001---
Fatigue08.01.01.002--
Miosis06.05.03.003; 17.02.11.002---
Nasal congestion22.04.04.001--
Orthostatic hypotension17.05.01.020; 24.06.03.004---
Somnolence17.02.04.006; 19.02.05.003--
Tachycardia02.03.02.007---
Gastrointestinal tract irritation07.08.03.008---
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