Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Phendimetrazine tartrate
Drug ID BADD_D01749
Description Phendimetrazine is a weight loss medication. Phendimetrazine is chemically related to amphetamines and is a Schedule III drug under the Convention on Psychotropic Substances and in the US since 1970.
Indications and Usage Used in the management of exogenous obesity as a short term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
Marketing Status approved; illicit
ATC Code Not Available
DrugBank ID DB01579
KEGG ID D02080
MeSH ID C100294
PubChem ID 120608
TTD Drug ID D0T6SU
NDC Product Code 51927-5043; 10702-077; 71335-2135; 17224-800; 0185-4057; 50090-5859; 68071-2605; 71335-0324; 71335-1840; 17337-0029; 63187-898; 66267-394; 68788-7236; 72989-409; 43063-510; 64850-440; 69543-409; 10702-078; 63629-2489; 50090-2235; 50090-3988; 50090-6552; 69543-410; 71335-0074; 72162-2044; 50090-0715; 10702-045
UNII 6985IP0T80
Synonyms phendimetrazine | X-Trozine | Di-Ap-Trol | Dyrexan | Hyrex | Melfiat | Obezine | phendimetrazine hydrochloride | phendimetrazine hydrochloride, (2S-trans)-isomer | phendimetrazine tartrate | phendimetrazine tartrate, (2S-trans(R-(R*,R*)))-isomer | phendimetrazine tartrate, (R-(R*,R*))-isomer | phendimetrazine, (2R-cis)-isomer | phendimetrazine, (2S-trans)-isomer | phendimetrazine, trans(+-)-isomer | Prelu-2 | Trimstat | Wehless | Weightrol | Adipost | Bontril
Chemical Information
Molecular Formula C16H23NO7
CAS Registry Number 50-58-8
SMILES CC1C(OCCN1C)C2=CC=CC=C2.C(C(C(=O)O)O)(C(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain upper07.01.05.003--
Agitation17.02.05.012; 19.06.02.001--
Blood pressure increased13.14.03.005---
Constipation07.02.02.001--
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dry mouth07.06.01.002--
Dysuria20.02.02.002--
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Headache17.14.01.001--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Insomnia17.15.03.002; 19.02.01.002--
Nausea07.01.07.001--
Palpitations02.11.04.012--
Pollakiuria20.02.02.007--
Restlessness17.02.05.021; 19.11.02.002--
Tachycardia02.03.02.007---
Tremor17.01.06.002--
Vision blurred06.02.06.007; 17.17.01.010--
Ischaemic cardiomyopathy02.04.01.004; 24.04.04.019---
Libido disorder19.08.03.004; 21.03.02.006---
Cardiac valve disease02.07.02.001---
Psychotic disorder19.03.01.002--
Device stimulation issue27.01.02.005---
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