Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Phencyclidine
Drug ID BADD_D01747
Description A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to ketamine in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (receptors, N-methyl-D-aspartate). As a drug of abuse, it is known as PCP and Angel Dust.
Indications and Usage Not Available
Marketing Status illicit
ATC Code Not Available
DrugBank ID DB03575
KEGG ID D05453
MeSH ID D010622
PubChem ID 6468
TTD Drug ID D0Q5PC
NDC Product Code Not Available
UNII J1DOI7UV76
Synonyms Phencyclidine | 1-(1-Phenylcyclohexyl)piperidine | Angel Dust | Dust, Angel | GP-121 | GP 121 | GP121 | Serylan | Phencyclidine Hydrochloride | Sernyl | CL-395 | CL 395 | CL395 | Phencyclidine Hydrobromide
Chemical Information
Molecular Formula C17H25N
CAS Registry Number 77-10-1
SMILES C1CCC(CC1)(C2=CC=CC=C2)N3CCCCC3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Anaphylactic shock10.01.07.002; 24.06.02.004---
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Asthma10.01.03.010; 22.03.01.002---
Bradycardia02.03.02.002---
Conjunctivitis06.04.01.002; 11.01.06.012--
Cough22.02.03.001--
Cyanosis02.11.04.004; 22.02.02.007; 23.06.04.005; 24.03.01.007--
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dyspnoea02.11.05.003; 22.02.01.004--
Erythema23.03.06.001---
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Gastrointestinal disorder07.11.01.001---
Hypotension24.06.03.002--
Lacrimation increased06.08.02.004--
Laryngeal oedema10.01.05.003; 22.04.02.001; 23.04.01.005--
Local reaction08.01.03.012---
Loss of consciousness17.02.04.004---
Nausea07.01.07.001--
Oedema peripheral02.05.04.007; 08.01.07.007; 14.05.06.011--
Pain08.01.08.004--
Pallor08.01.03.032; 23.03.03.031; 24.03.04.001---
Pruritus23.03.12.001--
Rhinitis11.01.13.004; 22.07.03.006--
Shock24.06.02.002---
Sneezing22.12.03.024--
Swelling08.01.03.015---
Syncope02.11.04.015; 17.02.04.008; 24.06.02.012--
Tachycardia02.03.02.007---
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