Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Pentosan polysulfate sodium
Drug ID BADD_D01729
Description Pentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.
Indications and Usage For the relief of bladder pain or discomfort associated with interstitial cystitis.
Marketing Status approved
ATC Code C05BA04; G04BX15
DrugBank ID DB00686
KEGG ID D05428
MeSH ID D010426
PubChem ID 156619446
TTD Drug ID D0F8CM
NDC Product Code 29967-0001; 52119-005; 10695-044; 51552-1589; 38779-2706; 71052-051; 60592-240; 62991-3120; 17359-3800; 69723-001; 42973-118; 49405-000; 50458-098; 46144-314; 51927-0052
UNII 914032762Y
Synonyms Pentosan Sulfuric Polyester | Polyester, Pentosan Sulfuric | Sulfuric Polyester, Pentosan | Pentosane Sulfuric Polyester | Polyester, Pentosane Sulfuric | Sulfuric Polyester, Pentosane | Xylan Sulfate | Sulfate, Xylan | Polypentose Sulfate | Sulfate, Polypentose | Polysulfated Xylan | Xylan, Polysulfated | Fibrocid | Hemoclar | HOE-BAY-946 | HOE BAY 946 | HOE-BAY 946 | BAY-946 | BAY 946 | HOE-946 | HOE 946 | Xylan SP54 | SP54, Xylan | Pentosan Polysulphate Sodium | Polysulphate Sodium, Pentosan | Sodium, Pentosan Polysulphate | Pentosan Polysulfate Sodium | Polysulfate Sodium, Pentosan | Sodium, Pentosan Polysulfate | PZ-68 | PZ 68 | PZ68 | SP-54 | SP 54 | SP54 | Tavan SP 54 | SP 54, Tavan | Elmiron | Pentosan Polysulfate | Polysulfate, Pentosan
Chemical Information
Molecular Formula C29H38Na10O50S9
CAS Registry Number 140207-93-8
SMILES COC1COC(C(C1OS(=O)(=O)[O-])OS(=O)(=O)[O-])OC2COC(C(C2OS(=O)(=O)[O-])OS(=O)(=O)[O -])OC3COC(C(C3OS(=O)(=O)[O-])OC4C(C(C(C(O4)C(=O)[O-])OC)OS(=O)(=O)[O-])OS(=O)(=O )[O-])OC5COC(C(C5OS(=O)(=O)[O-])OS(=O)(=O)[O-])OC.[Na+].[Na+].[Na+].[Na+].[Na+]. [Na+].[Na+].[Na+].[Na+].[Na+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Activated partial thromboplastin time prolonged13.01.02.001--
Alopecia23.02.02.001--
Amblyopia06.02.01.001---
Amenorrhoea05.05.01.002; 21.01.02.001--
Anaemia01.03.02.001--
Arthralgia15.01.02.001--
Colitis07.08.01.001--
Conjunctivitis06.04.01.002; 11.01.06.012--
Constipation07.02.02.001--
Depression19.15.01.001--
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dyspepsia07.01.02.001--
Dyspnoea02.11.05.003; 22.02.01.004--
Ecchymosis01.01.03.001; 23.06.01.001; 24.07.06.002---
Epistaxis22.04.03.001; 24.07.01.005--
Flatulence07.01.04.002--
Gastritis07.08.02.001--
Gingival bleeding07.09.07.001; 24.07.02.010---
Headache17.14.01.001--
Hepatic function abnormal09.01.02.001---
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hyperkinesia17.01.02.008---
Hypersensitivity10.01.03.003--
Insomnia17.15.03.002; 19.02.01.002--
Jaundice01.06.04.004; 09.01.01.004; 23.03.03.030---
Lacrimation increased06.08.02.004--
Leukopenia01.02.02.001---
Mouth ulceration07.05.06.004---
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