Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pentosan polysulfate
Drug ID BADD_D01728
Description Pentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.
Indications and Usage For the relief of bladder pain or discomfort associated with interstitial cystitis.
Marketing Status Prescription
ATC Code C05BA04; G04BX15
DrugBank ID DB00686
KEGG ID D05428
MeSH ID D010426
PubChem ID 37720
TTD Drug ID D0F8CM
NDC Product Code Not Available
Synonyms Pentosan Sulfuric Polyester | Polyester, Pentosan Sulfuric | Sulfuric Polyester, Pentosan | Pentosane Sulfuric Polyester | Polyester, Pentosane Sulfuric | Sulfuric Polyester, Pentosane | Xylan Sulfate | Sulfate, Xylan | Polypentose Sulfate | Sulfate, Polypentose | Polysulfated Xylan | Xylan, Polysulfated | Fibrocid | Hemoclar | HOE-BAY-946 | HOE BAY 946 | HOE-BAY 946 | BAY-946 | BAY 946 | HOE-946 | HOE 946 | Xylan SP54 | SP54, Xylan | Pentosan Polysulphate Sodium | Polysulphate Sodium, Pentosan | Sodium, Pentosan Polysulphate | Pentosan Polysulfate Sodium | Polysulfate Sodium, Pentosan | Sodium, Pentosan Polysulfate | PZ-68 | PZ 68 | PZ68 | SP-54 | SP 54 | SP54 | Tavan SP 54 | SP 54, Tavan | Elmiron | Pentosan Polysulfate | Polysulfate, Pentosan
Chemical Information
Molecular Formula C10H18O21S4
CAS Registry Number 37300-21-3
SMILES C1C(C(C(C(O1)OC2COC(C(C2OS(=O)(=O)O)OS(=O)(=O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)O
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.0020.000857%
Agitation17.02.05.012; 19.06.02.001--
Alopecia23.02.02.0010.003427%
Amblyopia06.02.01.001--Not Available
Amenorrhoea05.05.01.002; 21.01.02.001--
Anaemia01.03.02.001--
Angina pectoris02.02.02.002; 24.04.04.002--
Arthralgia15.01.02.001--
Chronic myeloid leukaemia01.10.07.001; 16.01.07.001--Not Available
Colitis07.08.01.0010.000857%
Conjunctivitis06.04.01.002; 11.01.06.012--
Constipation07.02.02.001--
Cystitis interstitial10.02.01.039; 20.03.02.0050.001142%Not Available
Dehydration14.05.05.0010.000571%
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness02.01.02.004; 17.02.05.003; 24.06.02.007--
Drug hypersensitivity10.01.01.0010.000857%Not Available
Dyspepsia07.01.02.001--
Dysphagia07.01.06.0030.001142%
Dyspnoea02.01.03.002; 22.02.01.004--
Ecchymosis01.01.03.001; 23.06.01.001; 24.07.06.002--Not Available
Epistaxis22.04.03.001; 24.07.01.005--
Feeling abnormal08.01.09.0140.000571%Not Available
Flatulence07.01.04.002--
Gastritis07.08.02.001--
Gastrointestinal pain07.01.05.005--
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