| Pharmaceutical Information |
| Drug Name |
Pentazocine hydrochloride |
| Drug ID |
BADD_D01719 |
| Description |
The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97) |
| Indications and Usage |
For the relief of moderate to severe pain. |
| Marketing Status |
approved; vet_approved |
| ATC Code |
N02AD01 |
| DrugBank ID |
DB00652
|
| KEGG ID |
D02227
|
| MeSH ID |
D010423
|
| PubChem ID |
441277
|
| TTD Drug ID |
D0W6DG
|
| NDC Product Code |
17337-0028; 48087-0077 |
| UNII |
A36BXO4PPX
|
| Synonyms |
Pentazocine | Lexir | Pentazocine Lactate | Lactate, Pentazocine | Talwin | Fortral | Pentazocine Hydrochloride | Hydrochloride, Pentazocine |
|
| Chemical Information |
| Molecular Formula |
C19H28ClNO |
| CAS Registry Number |
64024-15-3 |
| SMILES |
CC1C2CC3=C(C1(CCN2CC=C(C)C)C)C=C(C=C3)O.Cl |
| Chemical Structure |
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| ADRs Induced by Drug |
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*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
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| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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| Cardiovascular insufficiency | 02.11.01.011; 24.06.03.005 | - | - | - |
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