Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Patiromer
Drug ID BADD_D01686
Description Patiromer is a powder for suspension in water for oral administration, approved in the U.S. as Veltassa in October, 2015. Patiromer is supplied as patiromer sorbitex calcium which consists of the active moiety, patiromer, a non-absorbed potassium-binding polymer, and a calcium-sorbitol counterion. Each gram of patiromer is equivalent to a nominal amount of 2 grams of patiromer sorbitex calcium. The chemical name for patiromer sorbitex calcium is cross-linked polymer of calcium 2-fluoroprop-2-enoate with diethenylbenzene and octa-1,7-diene, combination with D-glucitol. Patiromer sorbitex calcium is an amorphous, free-flowing powder that is composed of individual spherical beads.
Indications and Usage For the treatment of hyperkalemia.
Marketing Status approved; investigational
ATC Code Not Available
DrugBank ID DB09263
KEGG ID D10148
MeSH ID C568789
PubChem ID Not Available
TTD Drug ID D0Z2YQ
NDC Product Code 53436-168; 53436-084; 53436-252
UNII 1FQ2RY5YHH
Synonyms patiromer | Veltassa | RLY 5016 | RLY5016 | RLY-5016
Chemical Information
Molecular Formula Not Available
CAS Registry Number 1260643-52-4
SMILES Not Available
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001---
Constipation07.02.02.001--
Diarrhoea07.02.01.001--
Flatulence07.01.04.002--
Hypokalaemia14.05.03.002--
Hypomagnesaemia14.04.02.001--
Lip oedema07.05.04.004; 10.01.05.004; 23.04.01.006---
Nausea07.01.07.001--
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