| Pharmaceutical Information |
| Drug Name |
Pasireotide diaspartate |
| Drug ID |
BADD_D01685 |
| Description |
Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease. |
| Indications and Usage |
For the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery has not been curative or is not an option. |
| Marketing Status |
approved |
| ATC Code |
H01CB05 |
| DrugBank ID |
DB06663
|
| KEGG ID |
D10497
|
| MeSH ID |
C517782
|
| PubChem ID |
70788982
|
| TTD Drug ID |
D0TV0C
|
| NDC Product Code |
71161-128; 71161-129; 55292-133; 55292-142; 55292-143; 55292-139; 55292-141; 71161-130; 71161-127; 71161-126; 55292-140; 55292-131; 55292-132 |
| UNII |
I4P76SY3N4
|
| Synonyms |
pasireotide | cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-d-tryptophyl-L-lysyl-4-o-benzyl-L-tyrosyl-L-phenylalanyl-) | SOM-230 | SOM 230 | SOM230 |
|
| Chemical Information |
| Molecular Formula |
C66H80N12O17 |
| CAS Registry Number |
820232-50-6 |
| SMILES |
C1C(CN2C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C2=O)CC3=CC=CC=C3)CC4=CC=C(C=C4
)OCC5=CC=CC=C5)CCCCN)CC6=CNC7=CC=CC=C76)C8=CC=CC=C8)OC(=O)NCCN.C(C(C(=O)O)N)C(=O
)O.C(C(C(=O)O)N)C(=O)O |
| Chemical Structure |
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| ADRs Induced by Drug |
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