| Pharmaceutical Information |
| Drug Name |
Paromomycin sulphate |
| Drug ID |
BADD_D01678 |
| Description |
An oligosaccharide antibiotic produced by various streptomyces. [PubChem] |
| Indications and Usage |
For the treatment of acute and chronic intestinal amebiasis (it is not effective in extraintestinal amebiasis). Also for the management of hepatic coma as adjunctive therapy. |
| Marketing Status |
approved; investigational |
| ATC Code |
A07AA06 |
| DrugBank ID |
DB01421
|
| KEGG ID |
D00868; D07467
|
| MeSH ID |
D010303
|
| PubChem ID |
165579
|
| TTD Drug ID |
D04NDM
|
| NDC Product Code |
Not Available |
| UNII |
61JJC8N5ZK
|
| Synonyms |
Paromomycin | Estomycin | Aminosidine | Neomycin E | Paramomycin | Paromomycin I | Catenulin | Hydroxymycin | Paromomycin Sulfate (1:1) | Paromomycin Sulfate (2:5) | Paromomycin Phosphate | Paromomycin, beta-D-Glucopyranosyl-Isomer | Paromomycin, beta D Glucopyranosyl Isomer | beta-D-Glucopyranosyl-Isomer Paromomycin | Humatin | Paromomycin Sulfate | Gabbromycin |
|
| Chemical Information |
| Molecular Formula |
C23H45N5O18S-2 |
| CAS Registry Number |
7542-37-2 |
| SMILES |
C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N
.[O-]S(=O)(=O)[O-] |
| Chemical Structure |
|
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| ADRs Induced by Drug |
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*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
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|
| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
| Abdominal pain | 07.01.05.002 | - | - | | | Diarrhoea | 07.02.01.001 | - | - | | | Nausea | 07.01.07.001 | - | - | |
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