Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Paricalcitol
Drug ID BADD_D01676
Description Paricalcitol is a synthetic vitamin D analog. Paricalcitol has been used to reduce parathyroid hormone levels. Paricalcitol is indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure.
Indications and Usage For treatment of secondary hyperparathyroidism associated with chronic kidney disease (CKD) Stage 3 and 4
Marketing Status approved; investigational
ATC Code H05BX02
DrugBank ID DB00910
KEGG ID D00930
MeSH ID C084656
PubChem ID 5281104
TTD Drug ID D0N1TP
NDC Product Code 0074-1658; 0074-4637; 0074-9036; 0143-9624; 65162-823; 65862-936; 70121-1035; 43598-565; 55150-213; 67457-379; 66499-0019; 16729-311; 43598-562; 55150-215; 68382-331; 65862-938; 67457-692; 69452-147; 10888-8103; 10888-8104; 11014-0334; 48943-0033; 58032-1001; 68513-1054; 49483-689; 55150-212; 68382-330; 69452-145; 70121-1033; 70121-1034; 10888-8102; 14474-021; 0143-9625; 49483-687; 65862-937; 11014-0048; 55111-663; 70121-1036; 58272-192; 0074-9037; 43598-563; 49483-688; 55111-665; 63629-2452; 67457-380; 16729-310; 25000-017; 0143-9596; 55150-214; 63629-2453; 65162-822; 67457-389; 69452-146; 25000-014; 43598-564; 55111-664; 65162-824; 11014-0053; 25000-012
UNII 6702D36OG5
Synonyms paricalcitol | 19-nor-1alpha,25-dihydroxyvitamin D2 | 19-nor-1,25-(OH)2D2 | Zemplar | paricalcitol-d6
Chemical Information
Molecular Formula C27H44O3
CAS Registry Number 131918-61-1
SMILES CC(C=CC(C)C(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3)O)O)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Lymphatic disorder01.09.01.003---
Musculoskeletal discomfort15.03.04.001---
Skin burning sensation17.02.06.009; 23.03.03.021---
Metabolic disorder14.11.01.0010.001962%-
Vasodilation procedure25.03.01.001---
Disturbance in sexual arousal19.08.04.003---
Angiopathy24.03.02.0070.002943%-
Adverse event08.06.01.0100.188360%-
Breast disorder21.05.04.004---
Cardiac disorder02.11.01.0030.445392%-
Connective tissue disorder10.04.04.026; 15.06.01.006---
Diabetic complication05.07.03.002; 14.07.03.0020.001962%-
Infarction24.04.02.0170.188360%-
Infestation11.09.01.001; 23.11.01.002---
Malnutrition14.03.02.0040.002943%-
Mediastinal disorder22.09.03.001---
Mental disorder19.07.01.002---
Poisoning12.03.01.004---
Decreased appetite08.01.09.028; 14.03.01.005--
Erectile dysfunction19.08.04.001; 21.03.01.007--
Ill-defined disorder08.01.03.049---
Inner ear disorder04.04.02.002---
Blood disorder01.05.01.004---
Psychotic disorder19.03.01.002--
Unevaluable event08.01.03.0510.072597%-
Arterial occlusive disease24.04.02.0210.002943%-
Hepatic enzyme abnormal13.03.04.026---
Chronic kidney disease20.01.03.0170.027469%
Adverse reaction08.06.01.018---
Oropharyngeal pain07.05.05.004; 22.12.03.016--
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ADReCS-Target
Drug Name ADR Term Target
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