| Pharmaceutical Information |
| Drug Name |
Papaverine hydrochloride |
| Drug ID |
BADD_D01671 |
| Description |
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels. |
| Indications and Usage |
For the treatment of impotence and vasospasms. |
| Marketing Status |
approved; investigational |
| ATC Code |
G04BE02; A03AD01 |
| DrugBank ID |
DB01113
|
| KEGG ID |
D02218
|
| MeSH ID |
D010208
|
| PubChem ID |
6084
|
| TTD Drug ID |
D0NJ3V
|
| NDC Product Code |
51927-0223; 51927-1775; 43235-0009; 62991-1203; 72516-024; 0517-4002; 49452-5000; 76003-0850; 14789-121; 38779-0454; 54288-142 |
| UNII |
23473EC6BQ
|
| Synonyms |
Papaverine | Pavatym | Pavabid | Cerespan | Papaverine Hydrochloride | Hydrochloride, Papaverine |
|
| Chemical Information |
| Molecular Formula |
C20H21NO4.ClH |
| CAS Registry Number |
61-25-6 |
| SMILES |
COC1=C(C=C(C=C1)CC2=NC=CC3=CC(=C(C=C32)OC)OC)OC.Cl |
| Chemical Structure |
|
|
| ADRs Induced by Drug |
|
|
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
|
|
|
