Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Nizatidine
Drug ID BADD_D01582
Description A histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.
Indications and Usage For the treatment of acid-reflux disorders (GERD), peptic ulcer disease, active benign gastric ulcer, and active duodenal ulcer.
Marketing Status Prescription; OTC; Discontinued
ATC Code A02BA04
DrugBank ID DB00585
KEGG ID D00440
MeSH ID D016567
PubChem ID 3033637
TTD Drug ID D0Q9DK
NDC Product Code 55111-310; 55111-311; 60846-301; 68071-1633; 63629-2769; 68462-425; 71335-0086; 63187-249; 0591-3137; 68071-5043; 65162-659; 0591-3138; 55111-011; 72643-018; 68462-426
Synonyms Nizatidine | N-(2-(((2-((Dimethylamino)methyl)-4-thiazolyl)methyl)thio)ethyl)-N'-methyl-2-nitro-1,1-ethenediamine | LY-139037 | LY 139037 | LY139037 | Axid
Chemical Information
Molecular Formula C12H21N5O2S2
CAS Registry Number 76963-41-2
SMILES CNC(=C[N+](=O)[O-])NCCSCC1=CSC(=N1)CN(C)C
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abnormal dreams17.15.02.001; 19.02.03.001--Not Available
Amblyopia06.02.01.001--Not Available
Anaemia01.03.02.001--
Anaphylactic shock10.01.07.002; 24.06.02.004--Not Available
Anxiety19.06.02.002--
Asthenia08.01.01.001--Not Available
Back pain15.03.04.005--
Blood uric acid increased13.02.04.001--Not Available
Body temperature increased13.15.01.001--Not Available
Bronchospasm10.01.03.012; 22.03.01.004--
Chest pain02.02.02.011; 08.01.08.002; 22.02.08.003--Not Available
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Cough22.02.03.001--
Dermatitis23.03.04.002--Not Available
Dermatitis exfoliative10.01.01.004; 23.03.07.001--
Diarrhoea07.02.01.001--
Dizziness02.01.02.004; 17.02.05.003; 24.06.02.007--
Dry mouth07.06.01.002--
Dyspepsia07.01.02.001--
Eosinophilia01.02.04.001--
Feeling abnormal08.01.09.014--Not Available
Flatulence07.01.04.002--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Gout14.09.01.001; 15.01.06.001--Not Available
Gynaecomastia05.05.02.003; 21.05.04.003--
Headache17.14.01.001--
Hepatitis09.01.07.004--Not Available
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