| Pharmaceutical Information |
| Drug Name |
Neostigmine methylsulfate |
| Drug ID |
BADD_D01554 |
| Description |
A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike physostigmine, does not cross the blood-brain barrier. |
| Indications and Usage |
Neostigmine is used for the symptomatic treatment of myasthenia gravis by improving muscle tone. |
| Marketing Status |
approved; vet_approved |
| ATC Code |
S01EB06; N07AA01 |
| DrugBank ID |
DB01400
|
| KEGG ID |
D00998
|
| MeSH ID |
D009388
|
| PubChem ID |
5824
|
| TTD Drug ID |
D08USJ
|
| NDC Product Code |
0641-6150; 75834-150; 23155-517; 65145-111; 68083-383; 71872-7143; 0641-6264; 38779-1851; 59651-243; 75834-149; 14445-015; 14593-903; 47621-305; 51662-1557; 63323-413; 68083-384; 70069-805; 70594-069; 71839-106; 72572-460; 0404-9925; 71288-501; 42023-188; 51754-1240; 52584-057; 70069-806; 70700-172; 0548-9601; 76045-383; 10695-033; 14501-0022; 23155-518; 65145-112; 70594-072; 71872-7271; 0641-6149; 0641-6265; 14778-0707; 42023-189; 51754-1210; 63323-415; 70121-1478; 72572-461; 0641-6240; 76045-214; 51927-0191; 66064-1020; 14445-414; 25021-611; 43598-945; 65219-811; 71872-7016; 72572-462; 45941-3053; 31722-995; 51754-1220; 70121-1479; 70516-0161; 25021-610; 70700-171; 0548-9602; 71288-500; 71839-105; 14445-413; 31722-994 |
| UNII |
98IMH7M386
|
| Synonyms |
Neostigmine | Synstigmin | Proserine | Prozerin | Polstigmine | Neostigmine Bromide | Bromide, Neostigmine | Syntostigmine | Neostigmine Methylsulfate | Methylsulfate, Neostigmine | Prostigmine | Prostigmin |
|
| Chemical Information |
| Molecular Formula |
C13H22N2O6S |
| CAS Registry Number |
51-60-5 |
| SMILES |
CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C.COS(=O)(=O)[O-] |
| Chemical Structure |
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| ADRs Induced by Drug |
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