Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Naftifine
Drug ID BADD_D01517
Description Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative for the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum.
Indications and Usage For the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum.
Marketing Status approved
ATC Code D01AE22
DrugBank ID DB00735
KEGG ID D08245
MeSH ID C029178
PubChem ID 47641
TTD Drug ID D00HPK
NDC Product Code Not Available
UNII 4FB1TON47A
Synonyms naftifine | naftifin | naftifine hydrochloride, (E)-isomer | naftifine hydrochloride | N-cinnamyl-N-methyl-1-naphthalenemethylamine hydrochloride
Chemical Information
Molecular Formula C21H21N
CAS Registry Number 65472-88-0
SMILES CN(CC=CC1=CC=CC=C1)CC2=CC=CC3=CC=CC=C32
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agranulocytosis01.02.03.001---
Application site erythema08.02.01.001; 12.07.01.001; 23.03.06.0050.003757%-
Application site pruritus08.02.01.005; 12.07.01.005; 23.03.12.0040.003757%-
Application site rash08.02.01.016; 12.07.01.016; 23.03.13.0080.003757%-
Application site reaction08.02.01.006; 12.07.01.0060.003757%-
Blister12.01.06.002; 23.03.01.0010.024420%-
Burning sensation08.01.09.029; 17.02.06.001---
Dermatitis23.03.04.002---
Dermatitis bullous23.03.01.002--
Dermatitis contact10.01.01.003; 12.03.01.040; 23.03.04.0040.005635%-
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Erythema23.03.06.0010.011271%-
Headache17.14.01.001--
Hypersensitivity10.01.03.0030.011271%
Leukopenia01.02.02.001---
Pain08.01.08.004--
Pain of skin23.03.03.003--
Pruritus23.03.12.0010.006188%
Rash23.03.13.0010.011271%-
Scab23.03.03.0040.002431%-
Skin exfoliation23.03.07.0030.015580%-
Swelling08.01.03.015---
Peripheral swelling02.05.04.015; 08.01.03.0530.003757%-
Application site papules08.02.01.025; 12.07.01.025; 23.03.03.0220.003757%-
Inflammation08.01.05.007; 10.02.01.089---
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ADReCS-Target
Drug Name ADR Term Target
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