| Pharmaceutical Information |
| Drug Name |
Nafcillin sodium |
| Drug ID |
BADD_D01516 |
| Description |
A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic drug. It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections caused by strains that are resistant to other penicillins, except those caused by MRSA. It may be used as a first-line therapy in Methicillin-Sensitive *Staphylococcus aureus* infections [A20360]. |
| Indications and Usage |
Indicated in the treatment of infections caused by penicillinase-producing staphylococci which have demonstrated susceptibility to the drug. |
| Marketing Status |
approved; investigational |
| ATC Code |
J01CF06 |
| DrugBank ID |
DB00607
|
| KEGG ID |
D00928
|
| MeSH ID |
D009254
|
| PubChem ID |
23667630
|
| TTD Drug ID |
D0A0JH
|
| NDC Product Code |
52946-0819; 25021-141; 55150-122; 70860-117; 63323-328; 66558-0202; 55150-124; 63323-327; 52946-0922; 25021-139; 25021-140; 55150-123; 70860-116; 61126-704; 70860-119 |
| UNII |
49G3001BCK
|
| Synonyms |
Nafcillin | Naphthamidopenicillin | Nafcil | Nafcillin Sodium | Sodium, Nafcillin | Nafcillin, Monosodium Salt, Anhydrous | Sodium Nafcillin | Nafcillin, Sodium |
|
| Chemical Information |
| Molecular Formula |
C21H21N2NaO5S |
| CAS Registry Number |
985-16-0 |
| SMILES |
CCOC1=C(C2=CC=CC=C2C=C1)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].[Na+] |
| Chemical Structure |
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| ADRs Induced by Drug |
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