Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Mycophenolic acid
Drug ID BADD_D01508
Description Mycophenolic acid is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older anti-proliferative azathioprine. It is usually used as part of triple therapy including a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. It is also useful in research for the selection of animal cells that express the E. coli gene coding for XGPRT (xanthine guanine phosphoribosyltransferase).
Indications and Usage For the prophylaxis of organ rejection in patients receiving allogeneic renal transplants, administered in combination with cyclosporine and corticosteroids.
Marketing Status approved
ATC Code L04AA06
DrugBank ID DB01024
KEGG ID D05096
MeSH ID D009173
PubChem ID 446541
TTD Drug ID D04FBR
NDC Product Code 72789-246; 68084-918; 70518-3218; 70748-218; 16729-189; 72789-247; 60505-2965; 67877-427; 70436-172; 0904-6785; 0078-0386; 16729-261; 70377-039; 0904-6786; 20076-0405; 50268-559; 60429-016; 60505-2966; 68084-907; 68254-5002; 50090-6492; 0378-4201; 52076-6215; 57885-0009; 60429-017; 67877-426; 70518-3255; 24979-161; 0378-4202; 70436-173; 70748-217; 65727-011; 0078-0385; 24979-160; 68254-5001; 70377-040; 51187-0004
UNII HU9DX48N0T
Synonyms Mycophenolic Acid | Mycophenolate Mofetil | Mofetil, Mycophenolate | Mycophenolic Acid Morpholinoethyl Ester | Cellcept | Mycophenolate Sodium | Sodium Mycophenolate | Mycophenolate, Sodium | Myfortic | Mycophenolate Mofetil Hydrochloride | Mofetil Hydrochloride, Mycophenolate | RS 61443 | RS-61443 | RS61443
Chemical Information
Molecular Formula C17H20O6
CAS Registry Number 24280-93-1
SMILES CC1=C2COC(=O)C2=C(C(=C1OC)CC=C(C)CCC(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cardiac arrest02.03.04.0010.001902%
Cardiac failure02.05.01.001--
Cardiac failure congestive02.05.01.0020.000951%-
Cardiovascular disorder02.11.01.010; 24.03.02.009---
Cataract06.06.01.001--
Cellulitis11.02.01.001; 23.11.02.004---
Cerebral haemorrhage17.08.01.003; 24.07.04.0010.001427%-
Cerebrovascular accident17.08.01.007; 24.03.05.0010.006848%
Cerebrovascular disorder17.08.02.002; 24.03.05.002---
Cheilitis07.05.01.001; 23.03.03.025--
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.003---
Chills08.01.09.001; 15.05.03.0160.003043%
Cholangitis09.02.01.002---
Cholestasis09.01.01.0010.002853%-
Coagulopathy01.01.02.001---
Colitis07.08.01.0010.002853%
Complications of transplant surgery12.02.09.007---
Confusional state17.02.03.005; 19.13.01.001--
Congenital anomaly03.02.01.001---
Conjunctivitis06.04.01.002; 11.01.06.012--
Constipation07.02.02.001--
Coordination abnormal17.02.02.004---
Cough22.02.03.0010.006848%
Cryptococcosis11.03.04.001---
Cushing's syndrome05.01.01.001; 14.11.01.007; 19.07.03.002; 24.08.04.001---
Cytomegalovirus infection11.05.01.002--
Deafness04.02.01.0010.000951%-
Death08.04.01.0010.036141%
Defaecation urgency07.02.04.0010.003234%-
Dehydration14.05.05.0010.006182%
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ADReCS-Target
Drug Name ADR Term Target
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