Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Mycophenolic acid
Drug ID BADD_D01508
Description Mycophenolic acid is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older anti-proliferative azathioprine. It is usually used as part of triple therapy including a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. It is also useful in research for the selection of animal cells that express the E. coli gene coding for XGPRT (xanthine guanine phosphoribosyltransferase).
Indications and Usage For the prophylaxis of organ rejection in patients receiving allogeneic renal transplants, administered in combination with cyclosporine and corticosteroids.
Marketing Status approved
ATC Code L04AA06
DrugBank ID DB01024
KEGG ID D05096
MeSH ID D009173
PubChem ID 446541
TTD Drug ID D04FBR
NDC Product Code 72789-246; 68084-918; 70518-3218; 70748-218; 16729-189; 72789-247; 60505-2965; 67877-427; 70436-172; 0904-6785; 0078-0386; 16729-261; 70377-039; 0904-6786; 20076-0405; 50268-559; 60429-016; 60505-2966; 68084-907; 68254-5002; 50090-6492; 0378-4201; 52076-6215; 57885-0009; 60429-017; 67877-426; 70518-3255; 24979-161; 0378-4202; 70436-173; 70748-217; 65727-011; 0078-0385; 24979-160; 68254-5001; 70377-040; 51187-0004
UNII HU9DX48N0T
Synonyms Mycophenolic Acid | Mycophenolate Mofetil | Mofetil, Mycophenolate | Mycophenolic Acid Morpholinoethyl Ester | Cellcept | Mycophenolate Sodium | Sodium Mycophenolate | Mycophenolate, Sodium | Myfortic | Mycophenolate Mofetil Hydrochloride | Mofetil Hydrochloride, Mycophenolate | RS 61443 | RS-61443 | RS61443
Chemical Information
Molecular Formula C17H20O6
CAS Registry Number 24280-93-1
SMILES CC1=C2COC(=O)C2=C(C(=C1OC)CC=C(C)CCC(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Decreased appetite08.01.09.028; 14.03.01.0050.005611%
Central nervous system stimulation25.04.01.001---
Erectile dysfunction19.08.04.001; 21.03.01.007--
Postoperative wound complication12.02.05.019---
Ill-defined disorder08.01.03.049---
Lacrimal disorder06.08.02.005---
Blood disorder01.05.01.004---
Immunodeficiency10.03.02.0020.000951%-
Atypical mycobacterial infection11.04.02.002---
Autoimmune disorder10.04.04.003--
Disease recurrence08.01.03.0500.002568%-
Psychotic disorder19.03.01.002--
Gastrointestinal obstruction07.13.01.005---
Hepatobiliary disease09.01.08.003---
Immunosuppression10.03.02.0010.002568%-
Hyperlipidaemia14.08.03.0010.001427%
Urine analysis abnormal13.13.02.008---
Renal impairment20.01.03.0100.004755%-
Respiratory tract infection11.01.08.017; 22.07.07.001---
Increased bronchial secretion22.12.01.002---
Device related infection08.07.01.005; 11.01.08.018--
Chronic kidney disease20.01.03.0170.002378%
Procedural pain08.01.08.009; 12.02.05.007---
Polyomavirus-associated nephropathy11.05.05.002; 12.02.09.037; 20.01.09.003---
Bone marrow failure01.03.03.0050.000951%
Urethral stenosis20.07.03.003---
Liver injury09.01.07.022; 12.01.17.0120.004280%-
Oropharyngeal discomfort07.05.05.008; 22.12.03.015---
Oropharyngeal pain07.05.05.004; 22.12.03.0160.003234%
X-linked lymphoproliferative syndrome01.13.02.003; 03.17.01.002; 10.03.01.003; 11.05.10.005; 16.21.02.003---
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ADReCS-Target
Drug Name ADR Term Target
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