Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Mycophenolic acid
Drug ID BADD_D01508
Description Mycophenolic acid is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older anti-proliferative azathioprine. It is usually used as part of triple therapy including a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. It is also useful in research for the selection of animal cells that express the E. coli gene coding for XGPRT (xanthine guanine phosphoribosyltransferase).
Indications and Usage For the prophylaxis of organ rejection in patients receiving allogeneic renal transplants, administered in combination with cyclosporine and corticosteroids.
Marketing Status approved
ATC Code L04AA06
DrugBank ID DB01024
KEGG ID D05096
MeSH ID D009173
PubChem ID 446541
TTD Drug ID D04FBR
NDC Product Code 72789-246; 68084-918; 70518-3218; 70748-218; 16729-189; 72789-247; 60505-2965; 67877-427; 70436-172; 0904-6785; 0078-0386; 16729-261; 70377-039; 0904-6786; 20076-0405; 50268-559; 60429-016; 60505-2966; 68084-907; 68254-5002; 50090-6492; 0378-4201; 52076-6215; 57885-0009; 60429-017; 67877-426; 70518-3255; 24979-161; 0378-4202; 70436-173; 70748-217; 65727-011; 0078-0385; 24979-160; 68254-5001; 70377-040; 51187-0004
UNII HU9DX48N0T
Synonyms Mycophenolic Acid | Mycophenolate Mofetil | Mofetil, Mycophenolate | Mycophenolic Acid Morpholinoethyl Ester | Cellcept | Mycophenolate Sodium | Sodium Mycophenolate | Mycophenolate, Sodium | Myfortic | Mycophenolate Mofetil Hydrochloride | Mofetil Hydrochloride, Mycophenolate | RS 61443 | RS-61443 | RS61443
Chemical Information
Molecular Formula C17H20O6
CAS Registry Number 24280-93-1
SMILES CC1=C2COC(=O)C2=C(C(=C1OC)CC=C(C)CCC(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Lymphatic disorder01.09.01.003---
Musculoskeletal discomfort15.03.04.001---
Nodule08.03.05.0020.000951%-
Affect lability19.04.01.001---
BK virus infection11.05.05.004---
Foetal death08.04.01.011; 18.01.02.003--
Haemorrhage24.07.01.002---
Cytomegalovirus syndrome11.05.01.005---
Paraesthesia oral07.05.05.035; 17.02.06.008---
Post procedural complication12.02.05.018---
Cytomegalovirus viraemia11.05.01.003---
Viraemia11.01.11.009--
Angiopathy24.03.02.007---
Blood alkaline phosphatase increased13.04.02.004--
Hot flush08.01.03.027; 21.02.02.001; 24.03.01.005--
Neurological symptom17.02.05.010---
Bacterial infection11.02.01.005---
Brain neoplasm16.30.01.003; 17.20.01.0030.000951%-
Breast disorder21.05.04.004---
Cardiac disorder02.11.01.003---
Connective tissue disorder10.04.04.026; 15.06.01.006---
Eyelid disorder06.08.03.010; 23.03.03.028---
Foetal disorder18.03.02.001---
Hereditary disorder03.02.01.007---
Infestation11.09.01.001; 23.11.01.002---
Inflammation08.01.05.007; 10.02.01.0890.000951%-
Lymphoproliferative disorder01.13.02.001; 16.21.02.001---
Malnutrition14.03.02.004---
Mediastinal disorder22.09.03.001---
Mental disorder19.07.01.002---
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ADReCS-Target
Drug Name ADR Term Target
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