Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Moexipril hydrochloride
Drug ID BADD_D01485
Description Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.
Indications and Usage For the treatment of hypertension.
Marketing Status approved
ATC Code C09AA13
DrugBank ID DB00691
KEGG ID D00623
MeSH ID C058302
PubChem ID 54889
TTD Drug ID D00HDU
NDC Product Code 68462-208; 17404-0018; 0093-0017; 0093-5150; 66039-838; 68462-209
UNII Q1UMG3UH45
Synonyms moexipril | 2-((1-ethoxycarbony)-3-phenylpropylamino-1-oxopropyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid | Fempress | moexipril hydrochloride | Univasc | Moex | Perdix | RS 10085 | RS-10085
Chemical Information
Molecular Formula C27H35ClN2O7
CAS Registry Number 82586-52-5
SMILES CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC(=C(C=C3CC2C(=O)O)OC)OC.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Alopecia23.02.02.001--
Angina pectoris02.02.02.002; 24.04.04.002--
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Anxiety19.06.02.002--
Arthralgia15.01.02.001--
Blood creatine increased13.13.01.001---
Blood creatinine increased13.13.01.004--
Blood urea increased13.13.01.006---
Blood uric acid increased13.02.04.001---
Bronchospasm10.01.03.012; 22.03.01.004--
Cerebrovascular accident17.08.01.007; 24.03.05.001--
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.003---
Constipation07.02.02.001--
Cough22.02.03.001--
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dry mouth07.06.01.002--
Dysgeusia07.14.03.001; 17.02.07.003--
Dyspepsia07.01.02.001--
Dyspnoea02.11.05.003; 22.02.01.004--
Eosinophilic pneumonia01.02.04.003; 22.01.01.004---
Fatigue08.01.01.002--
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Haemolytic anaemia01.06.03.002---
Headache17.14.01.001--
Hepatitis09.01.07.004---
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hyperkalaemia14.05.03.001--
Hyponatraemia14.05.04.002--
The 1th Page    1 2 3    Next   Last    Total 3 Pages
ADReCS-Target
Drug Name ADR Term Target
Tip:  Drug Name  ADR Term  Protein  Variation  Gene