Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Minoxidil
Drug ID BADD_D01473
Description A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Indications and Usage For the treatment of severe hypertension and in the topical treatment (regrowth) of androgenic alopecia in males and females and stabilisation of hair loss in patients with androgenic alopecia.
Marketing Status approved; investigational
ATC Code C02DC01; D11AX01
DrugBank ID DB00350
KEGG ID D00418
MeSH ID D008914
PubChem ID 4201
TTD Drug ID D0Y2CJ
NDC Product Code 73277-002; 82607-002; 83454-404; 0591-5642; 38779-0574; 11673-317; 30142-632; 0113-7798; 41163-798; 41250-749; 49035-905; 56062-798; 57483-540; 57483-542; 63940-385; 64942-2111; 68016-382; 69113-128; 71713-091; 71730-023; 72288-701; 72764-002; 72789-278; 79481-0070; 79903-072; 46204-0159; 54236-020; 11822-0114; 11822-0702; 30142-719; 51316-212; 53489-387; 57483-535; 63940-582; 63981-032; 69968-0031; 69968-0089; 71205-757; 71730-798; 72288-202; 72789-279; 72882-094; 81653-002; 82157-200; 82987-101; 83383-398; 0591-5643; 63934-007; 67438-020; 71052-063; 11509-0798; 11673-157; 11673-189; 11673-382; 11822-0606; 11822-0798; 0113-7202; 41250-202; 41250-428; 51326-160; 59450-211; 0363-0703; 68391-302; 69423-559; 69842-599; 70550-605; 72162-1490; 72484-096; 63629-1085; 65121-101; 68196-032; 71205-490; 71730-000; 72288-129; 72288-294; 72764-001; 81632-408; 82157-100; 82269-607; 40700-0008; 79572-022; 21130-273; 21130-750; 0113-1032; 49035-746; 49884-257; 50663-395; 53489-386; 56062-202; 56062-294; 63629-9299; 63629-9620; 64942-2110; 68084-204; 68391-294; 69113-129; 69423-586; 69842-598; 73277-001; 82429-200; 66219-0004; 67438-015; 11673-632; 11822-1033; 0113-0294; 0113-7129; 0113-7294; 37808-202; 41250-294; 51326-165; 56062-070; 0363-0032; 63629-1086; 0363-9090; 0363-9971; 63940-491; 63940-509; 63981-380; 63981-798; 65121-562; 68196-823; 69282-001; 69423-587; 81653-001; 81653-003; 81653-005; 17337-0027; 49452-4780; 51552-1334; 68981-036; 11673-707; 11822-0202; 11822-1323; 25280-006; 30142-294; 0113-7032; 37808-798; 43353-342; 51316-213; 63629-2230; 63629-2232; 0363-9091; 0363-9973; 63940-202; 69423-558; 69842-797; 70518-3419; 72484-095; 0009-5056; 62991-1105; 64162-0210; 11673-158; 11673-798; 11673-919; 0113-0798; 51326-161; 51672-2129; 55301-094; 56062-322; 59640-000; 59779-294; 0363-9972; 63940-032; 63981-294; 68788-8273; 69282-002; 71713-092; 71713-093; 71713-094; 72288-798; 81653-004; 51927-2885; 73005-0008; 80813-0022; 11673-431; 11822-0115; 41250-798; 42291-619; 49884-256; 51672-2128; 57483-530; 59726-115; 0363-2294; 0363-9970; 65121-102; 68196-469; 69968-0090; 71176-781; 71730-129; 71730-202; 71730-294; 82157-002; 82376-6006; 82376-6007; 0009-5230; 51552-0536; 11822-0129; 11822-1260; 25280-007; 0113-1129; 61269-094; 0363-1129; 0363-2798; 63629-2231; 63629-9433; 68016-006; 68084-205; 69968-0030; 71290-813; 80855-201; 81653-006; 82157-001; 82796-100; 10695-149; 76003-0748; 21130-163; 21130-819; 37808-833; 42291-618; 49035-294; 49539-001; 51326-166; 59450-210; 59726-116; 59779-202
UNII 5965120SH1
Synonyms Minoxidil | Rogaine | Regaine | U 10858 | Loniten
Chemical Information
Molecular Formula C9H15N5O
CAS Registry Number 38304-91-5
SMILES C1CCN(CC1)C2=NC(=N)N(C(=C2)N)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.0070.003998%
Drug hypersensitivity10.01.01.0010.009891%-
Dyspnoea02.11.05.003; 22.02.01.0040.004840%
Eczema23.03.04.006--
Electrocardiogram abnormal13.14.05.001---
Electrocardiogram ST segment13.14.05.035---
Erythema23.03.06.0010.003788%-
Erythema multiforme10.01.03.015; 23.03.01.003--
Eye irritation06.04.05.0030.000701%-
Eye swelling06.08.03.0030.001543%-
Face oedema08.01.07.003; 10.01.05.002; 23.04.01.0040.001754%
Feeling hot08.01.09.0090.001543%-
Fluid retention14.05.06.002; 20.01.02.003---
Flushing08.01.03.025; 23.06.05.003; 24.03.01.0020.003437%
Gastrointestinal disorder07.11.01.001---
Generalised oedema08.01.07.004; 14.05.06.0070.002104%
Gynaecomastia05.05.02.003; 21.05.04.0030.001052%
Hair colour changes23.02.06.0010.003577%
Hair disorder23.02.06.003---
Hair growth abnormal23.02.06.0060.007506%-
Hair texture abnormal23.02.06.0040.007506%
Headache17.14.01.0010.008347%
Heart rate increased13.14.04.002---
Hyperlactacidaemia14.01.01.0060.000701%-
Hypersensitivity10.01.03.0030.002595%
Hypertension24.08.02.0010.003086%
Hypertrichosis23.02.04.0020.011855%
Hypervolaemia02.05.04.019; 14.05.06.0030.001052%-
Hypotension24.06.03.0020.013749%
Irritability08.01.03.011; 19.04.02.0130.001543%
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