Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Midodrine hydrochloride
Drug ID BADD_D01462
Description An ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Indications and Usage For the treatment of symptomatic orthostatic hypotension (OH).
Marketing Status approved
ATC Code C01CA17
DrugBank ID DB00211
KEGG ID D01307
MeSH ID D008879
PubChem ID 18340
TTD Drug ID D02XJY
NDC Product Code 42291-561; 46708-339; 51407-389; 60505-1325; 68382-739; 70985-006; 71205-906; 0615-8383; 0615-8444; 50384-0800; 59285-043; 42291-560; 59651-246; 60687-409; 0378-1901; 71335-1433; 71335-2171; 71335-2174; 0615-8445; 70054-004; 49884-814; 64980-435; 63629-2346; 68382-737; 68382-738; 46708-338; 46708-340; 52817-325; 59651-248; 60687-398; 62332-340; 63629-2227; 63629-2348; 63739-145; 64980-433; 64980-434; 70771-1597; 72888-114; 0904-6818; 49884-849; 50268-562; 0245-0213; 0378-1903; 70700-157; 70771-1595; 70771-1596; 0904-6817; 14593-917; 50384-0810; 63190-0080; 51407-390; 0245-0211; 62332-338; 70985-007; 0615-8384; 0904-6819; 57451-1204; 63190-0720; 66583-0509; 50268-563; 51407-388; 55154-4174; 55154-5623; 59651-247; 70700-158; 70985-005; 71205-904; 71335-1705; 63190-0580; 42291-562; 49884-874; 51079-453; 52817-324; 55154-8086; 60505-1320; 62332-339; 70700-159; 71205-905; 72888-112; 60505-1321; 60687-387; 63629-2347; 0378-1902; 0615-8382; 0615-8443; 72888-113; 50268-561; 0245-0212; 52817-323
UNII 59JV96YTXV
Synonyms Midodrine | Midodrin | Midodrine Hydrochloride | Midodrine Monohydrochloride | Monohydrochloride, Midodrine | ProAmatine | Amatine | ST-1085 | ST 1085 | ST1085 | Gutron | Midon
Chemical Information
Molecular Formula C12H19ClN2O4
CAS Registry Number 43218-56-0
SMILES COC1=CC(=C(C=C1)OC)C(CNC(=O)CN)O.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001---
Anxiety19.06.02.002--
Aphthous ulcer07.05.06.002---
Asthenia08.01.01.001---
Back pain15.03.04.005--
Chills08.01.09.001; 15.05.03.016--
Confusional state17.02.03.005; 19.13.01.001--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dry mouth07.06.01.002--
Dry skin23.03.03.001--
Dyspepsia07.01.02.001--
Dysuria20.02.02.002--
Erythema multiforme10.01.03.015; 23.03.01.003--
Flatulence07.01.04.002--
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Head discomfort17.02.05.027---
Headache17.14.01.001--
Hyperaesthesia17.02.06.004; 23.03.03.080---
Hypertension24.08.02.001--
Insomnia17.15.03.002; 19.02.01.002--
Micturition urgency20.02.02.006--
Muscle spasms15.05.03.004--
Nausea07.01.07.001--
Nervousness19.06.02.003---
Pain08.01.08.004--
Paraesthesia17.02.06.005; 23.03.03.094--
Piloerection23.02.06.005---
Pollakiuria20.02.02.007--
Pruritus23.03.12.001--
Rash23.03.13.001---
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