Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Midodrine
Drug ID BADD_D01461
Description An ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Indications and Usage For the treatment of symptomatic orthostatic hypotension (OH).
Marketing Status approved
ATC Code C01CA17
DrugBank ID DB00211
KEGG ID D08220
MeSH ID D008879
PubChem ID 4195
TTD Drug ID D02XJY
NDC Product Code Not Available
UNII 6YE7PBM15H
Synonyms Midodrine | Midodrin | Midodrine Hydrochloride | Midodrine Monohydrochloride | Monohydrochloride, Midodrine | ProAmatine | Amatine | ST-1085 | ST 1085 | ST1085 | Gutron | Midon
Chemical Information
Molecular Formula C12H18N2O4
CAS Registry Number 42794-76-3
SMILES COC1=CC(=C(C=C1)OC)C(CNC(=O)CN)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001---
Abdominal pain07.01.05.002--
Agitation17.02.05.012; 19.06.02.001--
Anxiety19.06.02.002--
Aphthous ulcer07.05.06.002---
Asthenia08.01.01.001---
Back pain15.03.04.005--
Bradycardia02.03.02.0020.001296%-
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.0030.001750%-
Chills08.01.09.001; 15.05.03.016--
Confusional state17.02.03.005; 19.13.01.001--
Dermatitis23.03.04.002---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.0070.001426%
Drug interaction08.06.03.001---
Dry mouth07.06.01.002--
Dry skin23.03.03.001--
Dyspepsia07.01.02.001--
Dyspnoea02.11.05.003; 22.02.01.004--
Dysuria20.02.02.002--
Erythema multiforme10.01.03.015; 23.03.01.003--
Feeling abnormal08.01.09.014---
Flatulence07.01.04.002--
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Gait disturbance08.01.02.002; 15.03.05.013; 17.02.05.0160.001426%
Gastrointestinal disorder07.11.01.001---
Gastrointestinal pain07.01.05.005--
Generalised tonic-clonic seizure17.12.01.0020.002268%-
Hair disorder23.02.06.003---
Headache17.14.01.0010.003046%
Hepatic function abnormal09.01.02.001---
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