Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mexiletine
Drug ID BADD_D01452
Description Antiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.
Indications and Usage For the treatment of ventricular tachycardia and symptomatic premature ventricular beats, and prevention of ventricular fibrillation.
Marketing Status approved; investigational
ATC Code C01BB02
DrugBank ID DB00379
KEGG ID D08215
MeSH ID D008801
PubChem ID 4178
TTD Drug ID D0X0RI
NDC Product Code Not Available
UNII 1U511HHV4Z
Synonyms Mexiletine | Novo-Mexiletine | Novo Mexiletine | Mexiletine Hydrochloride | Mexitil | Mexitil PL | Mexityl | KO-1173 | KO 1173 | KO1173 | KOE-1173 | KOE 1173 | KOE1173 | Mexiletene
Chemical Information
Molecular Formula C11H17NO
CAS Registry Number 31828-71-4
SMILES CC1=C(C(=CC=C1)C)OCC(C)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hot flush08.01.03.027; 21.02.02.001; 24.03.01.005--
Erectile dysfunction19.08.04.001; 21.03.01.007--
Ill-defined disorder08.01.03.049---
Blood disorder01.05.01.004---
Psychotic disorder19.03.01.002--
Pulmonary toxicity12.03.01.013; 22.01.02.007---
Acute yellow liver atrophy09.01.07.026---
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