Drug Name |
Metyrosine |
Drug ID |
BADD_D01451 |
Description |
An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. (Martindale, The Extra Pharmacopoeia, 30th ed) |
Indications and Usage |
For use in the treatment of patients with pheochromocytoma, for preoperative preparation of patients for surgery, management of patients when surgery is contraindicated, and chronic treatment of patients with malignant pheochromocytoma. |
Marketing Status |
approved |
ATC Code |
C02KB01 |
DrugBank ID |
DB00765
|
KEGG ID |
D00762
|
MeSH ID |
D019805
|
PubChem ID |
441350
|
TTD Drug ID |
D0B3QM
|
NDC Product Code |
69575-4022; 68682-310; 71554-026; 69238-1621; 73223-007; 25010-305; 68022-7056; 67763-129 |
UNII |
DOQ0J0TPF7
|
Synonyms |
alpha-Methyltyrosine | alpha Methyltyrosine | alpha-Methyl-para-tyrosine | alpha Methyl para tyrosine | alpha-MPT | alpha MPT | alpha-Methyl-p-tyrosine | alpha Methyl p tyrosine | Metyrosine | alpha-Methyltyrosine, (L)-Isomer | Metirosine | Racemetirosine | alpha-Methyltyrosine, (D,L)-Isomer | alpha-Methyltyrosine, (+,-)-Isomer | DL-Tyrosine, alpha-methyl- | alpha-methyl- DL-Tyrosine | alpha-Methyltyrosine Hydrochloride | Hydrochloride, alpha-Methyltyrosine | alpha Methyltyrosine Hydrochloride | Demser |