Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methyltestosterone
Drug ID BADD_D01438
Description A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methyltestosterone is a schedule III drug in the US.
Indications and Usage Methyltestosterone is an anabolic steroid hormone used to treat men with a testosterone deficiency. It is also used in women to treat breast cancer, breast pain, swelling due to pregnancy, and with the addition of estrogen it can treat symptoms of menopause.
Marketing Status approved
ATC Code G03BA02; G03EK01
DrugBank ID DB06710
KEGG ID D00408
MeSH ID D008777
PubChem ID 6010
TTD Drug ID D0Z1XD
NDC Product Code 51552-0031; 62991-3177; 70954-255; 0115-1408; 22552-0020; 0115-7037; 43647-345; 51927-1028; 58159-070; 46439-8741; 60870-0232
UNII V9EFU16ZIF
Synonyms Methyltestosterone | 17beta-Methyltestosterone | 17beta Methyltestosterone | 17 beta Methyltestosterone | 17 beta-Hydroxy-17-methyl-4-androsten-3-one | 17 beta Hydroxy 17 methyl 4 androsten 3 one | 17 beta-Methyltestosterone | 17beta-Hydroxy-17-methyl-4-androsten-3-one | 17beta Hydroxy 17 methyl 4 androsten 3 one | 17-Epimethyltestosterone | 17 Epimethyltestosterone | Android (Methyltestoterone) | Android-10 | Android 10 | Android-25 | Android 25 | Android-5 | Android 5 | Mesteron | Mesterone | Methitest | Oreton | Testoviron | Testred | Virilon | 17-alpha-Methyltestosterone | 17 alpha Methyltestosterone | 17alpha-Methyl-Testosterone | 17alpha Methyl Testosterone | 17alpha-Methyltestosterone | 17alpha Methyltestosterone | Metandren
Chemical Information
Molecular Formula C20H30O2
CAS Registry Number 58-18-4
SMILES CC12CCC(=O)C=C1CCC3C2CCC4(C3CCC4(C)O)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acne23.02.01.001---
Alopecia23.02.02.001--
Amenorrhoea05.05.01.002; 21.01.02.001--
Anaphylactic shock10.01.07.002; 24.06.02.004---
Anaphylactoid reaction10.01.07.003; 24.06.03.007---
Anxiety19.06.02.002--
Azoospermia21.03.03.001--
Blood calcium13.11.01.041---
Blood chloride13.11.01.042---
Blood cholesterol increased13.12.01.002--
Blood gonadotrophin decreased13.10.03.001---
Blood phosphorus13.11.01.023---
Blood potassium13.11.01.032---
Coagulopathy01.01.02.001---
Depression19.15.01.001--
Embolism venous24.01.01.003---
Enlarged clitoris05.05.01.004; 21.08.02.001---
Erection increased19.08.04.002; 21.03.01.004---
Fluid retention14.05.06.002; 20.01.02.003---
Gynaecomastia05.05.02.003; 21.05.04.003--
Haemoglobin13.01.05.018---
Headache17.14.01.001--
Hepatic neoplasm09.04.03.001; 16.07.03.001---
Hirsutism05.05.01.005; 23.02.04.001--
Jaundice cholestatic09.01.01.005---
Libido decreased19.08.03.001; 21.03.02.005--
Libido increased19.08.03.002; 21.03.02.007--
Liver function test abnormal13.03.04.030---
Menstruation irregular05.05.01.008; 21.01.01.005--
Nausea07.01.07.001--
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