Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methylprednisolone sodium succinate
Drug ID BADD_D01436
Description A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Indications and Usage Not Available
Marketing Status approved
ATC Code Not Available
DrugBank ID DB14644
KEGG ID D00751
MeSH ID D008776
PubChem ID 23680530
TTD Drug ID Not Available
NDC Product Code 0404-9957; 71872-7061; 0009-0003; 0009-0047; 0143-9754; 43598-129; 0009-0698; 52584-039; 52584-047; 0009-0850; 55150-263; 55154-3940; 55154-3941; 63323-255; 43598-128; 70518-2023; 0143-9850; 63323-265; 0404-9958; 71872-7232; 55150-262; 55150-265; 70518-3684; 0009-0039; 0143-9753; 71872-7085; 0143-9851; 55154-3939; 55154-3944; 43598-127; 50090-0271; 63323-258; 0009-0018; 43598-130; 0009-0758; 55150-264
UNII LEC9GKY20K
Synonyms Methylprednisolone Hemisuccinate | Hemisuccinate, Methylprednisolone | Methylprednisolone Succinate | Succinate, Methylprednisolone | Urbason-Soluble | UrbasonSoluble | Solu-Medrol | Solumedrol | A-MethaPred | Methylprednisolone Sodium Succinate | Sodium Succinate, Methylprednisolone | Methylprednisolone Hemisuccinate Monosodium Salt | 6 alpha-Methylprednisolone Sodium Hemisuccinate | Methylprednisolone Sodium Hemisuccinate | Sodium Hemisuccinate, Methylprednisolone
Chemical Information
Molecular Formula C26H33NaO8
CAS Registry Number 2375-03-3
SMILES CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)COC(=O)CCC(=O)[O-])O.[Na+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Neuritis17.09.03.001---
Neuropathic arthropathy05.07.04.011; 14.07.04.011; 15.01.04.008; 17.09.03.008---
Neuropathy peripheral17.09.03.003---
Nitrogen balance negative13.13.01.010---
Oedema08.01.07.006; 14.05.06.010---
Osteonecrosis15.02.04.007; 24.04.05.004--
Osteoporosis14.04.04.002; 15.02.03.002--
Pancreatitis07.18.01.001--
Papilloedema06.09.02.002; 17.07.02.004; 24.03.07.001--
Paraesthesia17.02.06.005; 23.03.03.094--
Pathological fracture12.04.02.006; 15.08.02.008; 16.32.03.007---
Peptic ulcer07.04.07.001---
Personality change17.02.05.019; 19.05.01.006--
Petechiae01.01.03.002; 23.06.01.003; 24.07.06.004---
Pulmonary oedema02.05.02.003; 22.01.03.003--
Rash23.03.13.001---
Secondary adrenocortical insufficiency05.03.04.012; 14.11.01.014---
Seizure17.12.03.001--
Skin atrophy23.01.05.001--
Skin hyperpigmentation23.05.01.003--
Skin hypopigmentation23.05.02.003--
Skin striae23.01.05.002---
Small intestinal perforation07.04.06.006--
Sodium retention14.05.04.003---
Spermatozoa progressive motility abnormal13.20.04.011---
Spinal compression fracture12.04.04.001; 14.04.04.003; 15.08.05.004---
Syncope02.11.04.015; 17.02.04.008; 24.06.02.012--
Tachycardia02.03.02.007---
Tendon rupture12.01.07.003; 15.07.01.008---
Thrombophlebitis24.01.02.001---
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