Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Methylprednisolone hemisuccinate
Drug ID BADD_D01435
Description A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Indications and Usage Not Available
Marketing Status approved
ATC Code Not Available
DrugBank ID DB14644
KEGG ID D05000
MeSH ID D008776
PubChem ID 16923
TTD Drug ID Not Available
NDC Product Code 22552-0024; 57582-012; 82298-109; 24002-0015; 52128-152
UNII 5GMR90S4KN
Synonyms Methylprednisolone Hemisuccinate | Hemisuccinate, Methylprednisolone | Methylprednisolone Succinate | Succinate, Methylprednisolone | Urbason-Soluble | UrbasonSoluble | Solu-Medrol | Solumedrol | A-MethaPred | Methylprednisolone Sodium Succinate | Sodium Succinate, Methylprednisolone | Methylprednisolone Hemisuccinate Monosodium Salt | 6 alpha-Methylprednisolone Sodium Hemisuccinate | Methylprednisolone Sodium Hemisuccinate | Sodium Hemisuccinate, Methylprednisolone
Chemical Information
Molecular Formula C26H34O8
CAS Registry Number 2921-57-5
SMILES CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)COC(=O)CCC(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Leukoderma23.05.02.001---
Malaise08.01.01.003--
Mania19.16.02.002--
Meningitis11.01.03.001; 17.06.03.001--
Menstruation irregular05.05.01.008; 21.01.01.005--
Monoplegia17.01.04.003---
Mood swings19.04.03.001---
Muscular weakness15.05.06.001; 17.05.03.005--
Myalgia15.05.02.001--
Myocardial infarction02.02.02.007; 24.04.04.009--
Myocardial rupture02.04.02.002; 12.01.11.002---
Myopathy15.05.05.001---
Nausea07.01.07.001--
Neuropathic arthropathy05.07.04.011; 14.07.04.011; 15.01.04.008; 17.09.03.008---
Nitrogen balance negative13.13.01.010---
Oedema peripheral02.05.04.007; 08.01.07.007; 14.05.06.011--
Oesophagitis07.08.05.001--
Opportunistic infection11.01.08.007---
Optic neuritis06.04.08.002; 10.02.01.097; 17.04.05.001---
Osteonecrosis15.02.04.007; 24.04.05.004--
Osteoporosis14.04.04.002; 15.02.03.002--
Pancreatitis07.18.01.001--
Papilloedema06.09.02.002; 17.07.02.004; 24.03.07.001--
Paraplegia17.01.04.007---
Peptic ulcer07.04.07.001---
Peptic ulcer haemorrhage07.04.07.002; 24.07.02.015---
Peritonitis07.19.05.004; 11.01.07.007--
Personality change17.02.05.019; 19.05.01.006--
Petechiae01.01.03.002; 23.06.01.003; 24.07.06.004---
Pruritus23.03.12.001--
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