Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methazolamide
Drug ID BADD_D01410
Description A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
Indications and Usage For treatment of chronic open-angle glaucoma and acute angle-closure glaucoma
Marketing Status approved
ATC Code S01EC05
DrugBank ID DB00703
KEGG ID D00655
MeSH ID D008704
PubChem ID 4100
TTD Drug ID D0C2II
NDC Product Code 63629-1987; 42571-326; 69575-4008; 51224-124; 0574-0791; 24208-022; 62559-240; 68682-022; 11712-007; 24208-023; 51224-024; 55806-021; 68682-023; 71052-045; 11712-530; 42571-240; 51407-026; 0574-0790; 48954-472; 73377-208; 51407-027; 63629-1986; 63629-1958; 55806-020; 62559-241; 10695-171; 42571-239
UNII W733B0S9SD
Synonyms Methazolamide | N-Methylacetazolamide | N Methylacetazolamide
Chemical Information
Molecular Formula C5H8N4O3S2
CAS Registry Number 554-57-4
SMILES CC(=O)N=C1N(N=C(S1)S(=O)(=O)N)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pancytopenia01.03.03.003---
Paraesthesia17.02.06.005; 23.03.03.094--
Paralysis17.01.04.004---
Photosensitivity reaction23.03.09.003--
Polyuria20.02.03.002---
Rash23.03.13.001---
Seizure17.12.03.001--
Somnolence17.02.04.006; 19.02.05.003--
Stevens-Johnson syndrome10.01.01.045; 11.07.01.005; 12.03.01.014; 23.03.01.007--
Thrombocytopenic purpura01.08.01.003; 23.06.01.007---
Tinnitus04.04.01.002; 17.04.07.004--
Toxic epidermal necrolysis10.01.01.006; 11.07.01.006; 12.03.01.015; 23.03.01.008--
Urticaria10.01.06.001; 23.04.02.001--
Vertigo04.04.01.003; 17.02.12.002--
Vomiting07.01.07.003--
Hypoacusis04.02.01.006--
Urine output increased13.13.03.002---
Decreased appetite08.01.09.028; 14.03.01.005--
Ill-defined disorder08.01.03.049---
Blood disorder01.05.01.004---
Bone marrow failure01.03.03.005--
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