Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Meperidine hydrochloride
Drug ID BADD_D01385
Description A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Indications and Usage Used to control moderate to severe pain.
Marketing Status approved
ATC Code N02AB02
DrugBank ID DB00454
KEGG ID D01383
MeSH ID D008614
PubChem ID 5750
TTD Drug ID D00UYE
NDC Product Code 0641-6054; 42806-050; 0409-1179; 0409-1362; 42806-051; 0409-1181; 0409-1180; 0406-1585; 51927-1018; 0409-1178; 0409-1418; 0641-6052; 49452-0031; 65392-0923; 0409-1176; 0641-6053; 0054-3545
UNII N8E7F7Q170
Synonyms Meperidine | Pethidine | Isonipecain | Dolsin | Dolosal | Dolin | Operidine EPJ-I | Operidine EPJ I | Dolantin | Dolargan | Meperidine Hydrochloride | Lidol | Lydol | Demerol | Dolcontral
Chemical Information
Molecular Formula C15H22ClNO2
CAS Registry Number 50-13-5
SMILES CCOC(=O)C1(CCN(CC1)C)C2=CC=CC=C2.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agitation17.02.05.012; 19.06.02.001--
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Asthenia08.01.01.001---
Biliary colic09.02.01.001---
Bradycardia02.03.02.002---
Cardiac arrest02.03.04.001--
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Delirium19.13.02.001--
Disorientation17.02.05.015; 19.13.01.002---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dry mouth07.06.01.002--
Dyskinesia17.01.02.006--
Dysphoria19.04.02.004---
Euphoric mood19.04.02.006--
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Hallucination19.10.04.003--
Headache17.14.01.001--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypersensitivity10.01.03.003--
Hypotension24.06.03.002--
Injection site urticaria08.02.03.029; 10.01.06.003; 12.07.03.029; 23.04.02.003---
Mood altered19.04.02.007---
Muscle twitching15.05.03.005---
Myoclonus17.02.05.008---
Nausea07.01.07.001--
Palpitations02.11.04.012--
Pruritus23.03.12.001--
Rash23.03.13.001---
Respiratory arrest22.02.01.009---
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