Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mepenzolate bromide
Drug ID BADD_D01383
Description Mepenzolate is a post-ganglionic parasympathetic inhibitor. It decreases gastric acid and pepsin secretion and suppresses spontaneous contractions of the colon. Mepenzolate diminishes gastric acid and pepsin secretion. Mepenzolate also suppresses spontaneous contractions of the colon. Pharmacologically, it is a post-ganglionic parasympathetic inhibitor. It has not been shown to be effective in contributing to the healing of peptic ulcer, decreasing the rate of recurrence, or preventing complications.
Indications and Usage For use as adjunctive therapy in the treatment of peptic ulcer. It has not been shown to be effective in contributing to the healing of peptic ulcer, decreasing the rate of recurrence, or preventing complications.
Marketing Status approved
ATC Code A03AB12
DrugBank ID DB04843
KEGG ID D00720
MeSH ID C005101
PubChem ID 6461
TTD Drug ID D0FV3V
NDC Product Code Not Available
UNII APX8D32IX1
Synonyms mepenzolic acid | mepenzolate iodide | mepenzolate bromide | mepenzolic acid, bromine salt | N-methyl-3-piperidylbenzilate methyl bromide | mepenzolate | Cantil | mepenzolate bromide, (+-)-isomer | mepenzolic acid, bromine salt, 1-(methyl-(14)C)-labeled
Chemical Information
Molecular Formula C21H26BrNO3
CAS Registry Number 76-90-4
SMILES C[N+]1(CCCC(C1)OC(=O)C(C2=CC=CC=C2)(C3=CC=CC=C3)O)C.[Br-]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Ageusia07.14.03.003; 17.02.07.001---
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Asthenia08.01.01.001---
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Cycloplegia06.05.03.002; 17.17.02.003---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dry mouth07.06.01.002--
Headache17.14.01.001--
Hypohidrosis08.01.03.029; 23.02.03.005--
Insomnia17.15.03.002; 19.02.01.002--
Intraocular pressure increased13.07.04.002---
Mydriasis06.05.03.004; 17.02.11.003---
Nausea07.01.07.001--
Nervousness19.06.02.003---
Palpitations02.11.04.012--
Somnolence17.02.04.006; 19.02.05.003--
Tachycardia02.03.02.007---
Urinary hesitation20.02.02.009---
Urinary retention20.02.02.011--
Urticaria10.01.06.001; 23.04.02.001--
Vision blurred06.02.06.007; 17.17.01.010--
Vomiting07.01.07.003--
Erectile dysfunction19.08.04.001; 21.03.01.007--
Lactation insufficiency18.06.02.006; 21.05.02.006---
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