Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mebendazole
Drug ID BADD_D01353
Description A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Indications and Usage For the treatment of Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections.
Marketing Status approved; vet_approved
ATC Code P02CA01
DrugBank ID DB00643
KEGG ID D00368
MeSH ID D008463
PubChem ID 4030
TTD Drug ID D0J1MI
NDC Product Code 59285-011; 90027-001; 73309-120; 71052-168; 12578-618; 64896-669; 72643-035; 82891-003; 69766-038; 50458-675; 53104-7510
UNII 81G6I5V05I
Synonyms Mebendazole | Vermidil | Wormkuur | Anti-Worm | Anti Worm | Bantenol | Banworm | Boots Threadworm Treatment | Lomper | Madicure | Mebendan | Mebenvet | Pripsen Mebendazole | R17635 | Sqworm | Sufil | Telmin | Vermicol | Surfont | Vermox
Chemical Information
Molecular Formula C16H13N3O3
CAS Registry Number 31431-39-7
SMILES COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CC=C3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.0020.036733%
Abdominal pain upper07.01.05.0030.007871%
Abortion spontaneous18.01.04.0010.005248%-
Agranulocytosis01.02.03.001---
Alanine aminotransferase increased13.03.04.005--
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.0010.005248%-
Aspartate aminotransferase increased13.03.04.011--
Asthenia08.01.01.0010.005248%-
Ataxia08.01.02.004; 17.02.02.0010.005248%
Confusional state17.02.03.005; 19.13.01.0010.005248%
Dehydration14.05.05.0010.005248%
Dermatitis23.03.04.002---
Diarrhoea07.02.01.0010.018367%
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.0070.034109%
Dyspnoea02.11.05.003; 22.02.01.0040.005248%
Fatigue08.01.01.0020.010495%
Gamma-glutamyltransferase increased13.03.04.024--
Gastrointestinal disorder07.11.01.0010.005248%-
Gastrointestinal pain07.01.05.005--
Hallucination19.10.04.0030.005248%
Headache17.14.01.0010.013119%
Hepatitis09.01.07.004---
Hepatocellular injury09.01.07.0080.005248%-
Hyperhidrosis08.01.03.028; 23.02.03.0040.005248%
Hypersensitivity10.01.03.003--
Intentional self-injury12.01.08.036; 19.12.01.0020.007871%-
Malaise08.01.01.0030.005248%
Muscular weakness15.05.06.001; 17.05.03.0050.020990%
Nausea07.01.07.0010.037783%
Neutropenia01.02.03.004---
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